ID A0A2I3RDJ4_PANTR Unreviewed; 590 AA.
AC A0A2I3RDJ4; A0A2J8QD03;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Stress-induced-phosphoprotein 1 {ECO:0000256|ARBA:ARBA00026193};
DE AltName: Full=Hsc70/Hsp90-organizing protein {ECO:0000256|ARBA:ARBA00032536};
GN Name=STIP1 {ECO:0000313|Ensembl:ENSPTRP00000062738.1,
GN ECO:0000313|VGNC:VGNC:3049};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000062738.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000062738.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000062738.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04016207; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04016208; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC175468; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC192585; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3RDJ4; -.
DR SMR; A0A2I3RDJ4; -.
DR STRING; 9598.ENSPTRP00000062738; -.
DR PaxDb; 9598-ENSPTRP00000042319; -.
DR Ensembl; ENSPTRT00000111146.1; ENSPTRP00000062738.1; ENSPTRG00000003820.6.
DR VGNC; VGNC:3049; STIP1.
DR GeneTree; ENSGT00940000154911; -.
DR InParanoid; A0A2I3RDJ4; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000003820; Expressed in lung and 22 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0101031; C:protein folding chaperone complex; IEA:Ensembl.
DR GO; GO:0051879; F:Hsp90 protein binding; IEA:Ensembl.
DR Gene3D; 1.10.260.100; -; 2.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR041243; STI1/HOP_DP.
DR InterPro; IPR006636; STI1_HS-bd.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR013105; TPR_2.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR22904:SF523; STRESS-INDUCED-PHOSPHOPROTEIN 1; 1.
DR PANTHER; PTHR22904; TPR REPEAT CONTAINING PROTEIN; 1.
DR Pfam; PF17830; STI1-HOP_DP; 2.
DR Pfam; PF13414; TPR_11; 2.
DR Pfam; PF13424; TPR_12; 1.
DR Pfam; PF07719; TPR_2; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00727; STI1; 2.
DR SMART; SM00028; TPR; 9.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 7.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 51..84
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 85..118
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 177..216
FT /note="STI1"
FT /evidence="ECO:0000259|SMART:SM00727"
FT REPEAT 272..305
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 347..380
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 407..440
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 441..474
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 475..508
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT DOMAIN 539..578
FT /note="STI1"
FT /evidence="ECO:0000259|SMART:SM00727"
FT REGION 239..269
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 255..269
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 590 AA; 68080 MW; 76F4C7A16BFCBCA0 CRC64;
MESGSPMGEV EISRTIRTNG RGQRGYDWQC KRPIRVAEVR SSLHSWSLRW VNELKEKGNK
ALSVGNIDDA LQCYSEAIKL DPHNHVLYSN RSAAYAKKGD YQKAYEDGCK TVDLKPDWGK
GYSRKAAALE FLNRFEEAKR TYEEGLKHEA NNPQLKEGLQ NMEARLAERK FMNPFNMPNL
YQKLESDPRT RTLLSDPTYR ELIEQLRNKP SDLGTKLQDP RIMTTLSVLL GVDLGSMDEE
EEIATPPPPP PPKKETKPEP MEEDLPENKK QALKEKELGN DAYKKKDFDT ALKHYDKAKE
LDPTNMTYIT NQAAVYFEKG DYNKCRELCE KAIEVGRENR EDYRQIAKAY ARIGNSYFKE
EKYKDAIHFY NKSLAEHRTP DVLKKCQQAE KILKEQERLA YINPDLALEE KNKGNECFQK
GDYPQAMKHY TEAIKRNPKD AKLYSNRAAC YTKLLEFQLA LKDCEECIQL EPTFIKGYTR
KAAALEAMKD YTKAMDVYQK ALDLDSSCKE AADGYQRCMM AQYNRHDSPE DVKRRAMADP
EVQQIMSDPA MRLILEQMQK DPQALSEHLK NPVIAQKIQK LMDVGLIAIR
//
