ID A0A2I3RG16_PANTR Unreviewed; 301 AA.
AC A0A2I3RG16;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Palmitoyl-protein thioesterase 2 {ECO:0000313|Ensembl:ENSPTRP00000063636.1};
GN Name=PPT2 {ECO:0000313|VGNC:VGNC:11185};
GN Synonyms=EGFL8 {ECO:0000313|Ensembl:ENSPTRP00000063636.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000063636.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000063636.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000063636.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the palmitoyl-protein thioesterase family.
CC {ECO:0000256|ARBA:ARBA00010758}.
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DR EMBL; AC190421; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3RG16; -.
DR Ensembl; ENSPTRT00000088769.1; ENSPTRP00000063636.1; ENSPTRG00000018008.7.
DR VGNC; VGNC:11185; PPT2.
DR GeneTree; ENSGT00940000155779; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018008; Expressed in cerebellar cortex and 21 other cell types or tissues.
DR GO; GO:0098599; F:palmitoyl hydrolase activity; IEA:InterPro.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002472; Palm_thioest.
DR PANTHER; PTHR11247:SF27; LYSOSOMAL THIOESTERASE PPT2; 1.
DR PANTHER; PTHR11247; PALMITOYL-PROTEIN THIOESTERASE/DOLICHYLDIPHOSPHATASE 1; 1.
DR Pfam; PF02089; Palm_thioest; 1.
DR PRINTS; PR00414; PPTHIESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..301
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014142185"
SQ SEQUENCE 301 AA; 34138 MW; 80825299D4599E13 CRC64;
MLGLWGQRLP AAWVLLLLPF LPLLLLAAPG PHRASYKPVI VVHGLFDSSY SFRHLLEYIN
ETHPGTVVTV LDLFDGRESL RPLWEQVQGF REAVVPIMAK APQGLHLICY SQGGLVCRAL
LSVMDDHNVD SFISLSSPQM GQYGDTDYLK WLFPTSMRSN LYRICYSPWG QEFSICNYWH
DPHHDDLYLN ASSFLALING ERDHPNATVW RKNFLRVGHL VLIGGPDDGV ITPWQSSFFG
FYDANETVLE MEEQLPARPT HQSELLLLRL VCLKPPRRKK PACRVQRQSE SWGPGLSCAL
S
//
