ID A0A2I3RI14_PANTR Unreviewed; 330 AA.
AC A0A2I3RI14;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Carnosine N-methyltransferase {ECO:0000256|ARBA:ARBA00015448};
DE EC=2.1.1.22 {ECO:0000256|ARBA:ARBA00012003};
GN Name=CARNMT1 {ECO:0000313|Ensembl:ENSPTRP00000064323.1,
GN ECO:0000313|VGNC:VGNC:13858};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000064323.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000064323.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000064323.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the carnosine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010086}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04029827; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016816454.1; XM_016960965.1.
DR RefSeq; XP_016816455.1; XM_016960966.1.
DR RefSeq; XP_016816456.1; XM_016960967.1.
DR AlphaFoldDB; A0A2I3RI14; -.
DR Ensembl; ENSPTRT00000080224.1; ENSPTRP00000064323.1; ENSPTRG00000021028.7.
DR GeneID; 472958; -.
DR CTD; 138199; -.
DR VGNC; VGNC:13858; CARNMT1.
DR GeneTree; ENSGT00390000005323; -.
DR OrthoDB; 167229at2759; -.
DR Proteomes; UP000002277; Chromosome 9.
DR Bgee; ENSPTRG00000021028; Expressed in fibroblast and 21 other cell types or tissues.
DR GO; GO:0030735; F:carnosine N-methyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR012901; CARME.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR12303:SF6; CARNOSINE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR12303; UNCHARACTERIZED; 1.
DR Pfam; PF07942; CARME; 1.
DR SMART; SM01296; N2227; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
SQ SEQUENCE 330 AA; 38591 MW; 0C02D2C20A60B63D CRC64;
MHERVNRTER QFRSLPANQQ KLLPQFLLHL DKIRKCIDHN QEILLTIVND CIHMFENKEY
GEDGNGKIMP ASTFDMDKLK STLKQFVRDW SETGKAERDA CYQPIIKEIL KNFPKERWDP
SKVNILVPGA GLGRLAWEIA MLGYACQGNE WSFFMLFSSN FVLNRCSEIN KYKLYPWIHQ
FSNNRRSADQ IRPIFFPDVD PHSLPPGSNF SMTAGDFQEI YSECNTWDCI ATCFFIDTAH
NVIDYIDTIW KILKPGGIWI NLGPLLYHFE NLANELSIEL SYEDIKNVVL QYGFKVEVEK
ESVLSTYTVN DLSMMKYYYE CVLFVVRKPQ
//
