ID   A0A2I3RIG2_PANTR        Unreviewed;       658 AA.
AC   A0A2I3RIG2; A0A2J8NQN4;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=Thrombospondin type 1 domain containing 4 {ECO:0000313|Ensembl:ENSPTRP00000064473.1};
GN   Name=THSD4 {ECO:0000313|Ensembl:ENSPTRP00000064473.1,
GN   ECO:0000313|VGNC:VGNC:2461};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000064473.1, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000064473.1, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000064473.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AACZ04064647; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04064648; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04064649; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04064650; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04064651; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; XP_009427743.1; XM_009429468.2.
DR   AlphaFoldDB; A0A2I3RIG2; -.
DR   Ensembl; ENSPTRT00000100445.1; ENSPTRP00000064473.1; ENSPTRG00000007240.6.
DR   GeneID; 467719; -.
DR   CTD; 79875; -.
DR   VGNC; VGNC:2461; THSD4.
DR   GeneTree; ENSGT00940000156594; -.
DR   OrthoDB; 2910701at2759; -.
DR   Proteomes; UP000002277; Chromosome 15.
DR   Bgee; ENSPTRG00000007240; Expressed in lung and 19 other cell types or tissues.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.830; -; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 6.
DR   InterPro; IPR010294; ADAMTS_spacer1.
DR   InterPro; IPR010909; PLAC.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR   PANTHER; PTHR13723:SF281; NO LONG NERVE CORD, ISOFORM C; 1.
DR   Pfam; PF05986; ADAMTS_spacer1; 1.
DR   Pfam; PF08686; PLAC; 1.
DR   Pfam; PF19030; TSP1_ADAMTS; 6.
DR   SMART; SM00209; TSP1; 6.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR   PROSITE; PS50900; PLAC; 1.
DR   PROSITE; PS50092; TSP1; 5.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..658
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5015081175"
FT   DOMAIN          611..648
FT                   /note="PLAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50900"
FT   REGION          174..263
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        196..218
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   658 AA;  73429 MW;  25C62921E7B90E67 CRC64;
     MFVSYLILTL LHVQTAVLAR PGGESIGCDD YLGSDKVVDK CGVCGGDNTG CQVVSGVFKH
     ALTSLGYHRV VEIPEGATKI NITEMYKSNN YLALRSRSGR SIINGNWAID RPGKYEGGGT
     MFTYKRPNEI SSTAGESFLA EGPTNEILDV YMIHQQPNPG VHYEYVIMGT NAISPQVPPH
     RRPGEPFNGQ MVTEGRSQEE GEEKGRNEEK EDLRGEAPEM FTSESAQTFP VRHPDRFSPR
     RPDNLVPPAP QPPRRSRDHN WKQLGTTECS TTCGKGSQYP IFRCVHRSTH EEAPESYCDS
     SMKPTPEEEP CNIFPCPAFW DIGEWSECSK TCGLGMQHRQ VLCRQVYANR SLTVQPYRCQ
     HLEKPETTST CQLKICSEWQ IRTDWTSCSV PCGVGQRTRD VKCVSNIGDV VDDEECNMKL
     RPNDIENCDM GPCAKSWFLT EWSERCSAEC GAGVRTRSVV CMTNHVSSLP LEGCGNNRPA
     EATPCDNGPC TGKVEWFAGS WSQCSIECGS GTQQREVICV RKNADTFEVL DPSECSFLEK
     PPSQQSCHLK PCGAKWFSTE WSMCSKSCQG GFRVREVRCL SDDMTLSNLC DPQLKPEERE
     SCNPQDCVPE VDENCKDKYY NCNVVVQARL CVYNYYKTAC CASCTRVANR QTGFLGSR
//