ID A0A2I3RPH4_PANTR Unreviewed; 188 AA.
AC A0A2I3RPH4; A0A2J8N4Q1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Coenzyme Q-binding protein COQ10 homolog B, mitochondrial {ECO:0000256|ARBA:ARBA00039620};
GN Name=COQ10B {ECO:0000313|Ensembl:ENSPTRP00000066594.1,
GN ECO:0000313|VGNC:VGNC:145};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000066594.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000066594.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000066594.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes. {ECO:0000256|ARBA:ARBA00024947}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000256|ARBA:ARBA00011814}.
CC -!- SIMILARITY: Belongs to the COQ10 family.
CC {ECO:0000256|ARBA:ARBA00006885}.
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DR EMBL; AACZ04058653; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016805764.1; XM_016950275.1.
DR AlphaFoldDB; A0A2I3RPH4; -.
DR Ensembl; ENSPTRT00000087439.1; ENSPTRP00000066594.1; ENSPTRG00000012772.4.
DR VGNC; VGNC:145; COQ10B.
DR GeneTree; ENSGT00940000155367; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000012772; Expressed in lung and 22 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-KW.
DR GO; GO:0048039; F:ubiquinone binding; IEA:InterPro.
DR GO; GO:0045333; P:cellular respiration; IEA:InterPro.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:InterPro.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901:SF9; COENZYME Q-BINDING PROTEIN COQ10 HOMOLOG B, MITOCHONDRIAL; 1.
DR PANTHER; PTHR12901; SPERM PROTEIN HOMOLOG; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
DR SUPFAM; SSF55961; Bet v1-like; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 36..163
FT /note="Coenzyme Q-binding protein COQ10 START"
FT /evidence="ECO:0000259|Pfam:PF03364"
SQ SEQUENCE 188 AA; 21352 MW; BD085B50C4FE5A6E CRC64;
MAARTGHTAL RRVVSGCRPK SATAAGAQAP LRNGRYSMQE MYDVVSGVED YKHFVPWCKK
SDVISKRSGY CKTRLEIGFP PVLERYTSVV TLVKPHLVKA SCTDGRLFNH LETIWRFSPG
LPGYPRTCTL DFSISFEFRS LLHSQLATLF FDEVVKQMVA AFERRACKLY GPETNIPREL
MLHEVHHT
//
