ID A0A2I3RRN6_PANTR Unreviewed; 142 AA.
AC A0A2I3RRN6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Protein cornichon homolog 4 {ECO:0000256|ARBA:ARBA00040249};
DE AltName: Full=Cornichon family AMPA receptor auxiliary protein 4 {ECO:0000256|ARBA:ARBA00041368};
GN Name=CNIH4 {ECO:0000313|Ensembl:ENSPTRP00000067358.1,
GN ECO:0000313|VGNC:VGNC:506};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000067358.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000067358.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000067358.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum-Golgi intermediate
CC compartment {ECO:0000256|ARBA:ARBA00004399}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the cornichon family.
CC {ECO:0000256|ARBA:ARBA00010095}.
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DR EMBL; AACZ04040695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3RRN6; -.
DR PaxDb; 9598-ENSPTRP00000003397; -.
DR Ensembl; ENSPTRT00000082689.1; ENSPTRP00000067358.1; ENSPTRG00000002025.7.
DR VGNC; VGNC:506; CNIH4.
DR GeneTree; ENSGT00950000182834; -.
DR InParanoid; A0A2I3RRN6; -.
DR OMA; WIAFLLN; -.
DR Proteomes; UP000002277; Chromosome 1.
DR Bgee; ENSPTRG00000002025; Expressed in fibroblast and 22 other cell types or tissues.
DR GO; GO:0030134; C:COPII-coated ER to Golgi transport vesicle; IBA:GO_Central.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IBA:GO_Central.
DR GO; GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IEA:UniProtKB-SubCell.
DR GO; GO:0031730; F:CCR5 chemokine receptor binding; IEA:Ensembl.
DR GO; GO:0006888; P:endoplasmic reticulum to Golgi vesicle-mediated transport; IBA:GO_Central.
DR InterPro; IPR003377; Cornichon.
DR PANTHER; PTHR12290; CORNICHON-RELATED; 1.
DR PANTHER; PTHR12290:SF19; PROTEIN CORNICHON HOMOLOG 4; 1.
DR Pfam; PF03311; Cornichon; 1.
DR SMART; SM01398; Cornichon; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 7..28
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 55..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 121..140
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 142 AA; 16544 MW; 441A5CC2A811F2C3 CRC64;
RRRMEAVVFV FSLLDCCALI FLSVYFIITL SDLECDYINA RSCCSKLNKW VIPELIGHTI
VTVLLLISLH WFIFLLNLPV ATWNIYRYIM VPSGNMGVFD PTEIHNRGQL KSHMKEAMIK
LGFHLLCFFM YLYSMILALI ND
//
