ID A0A2I3RUI9_PANTR Unreviewed; 408 AA.
AC A0A2I3RUI9; A0A2J8QC10;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
GN Name=FRMD8 {ECO:0000313|Ensembl:ENSPTRP00000068381.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000068381.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000068381.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000068381.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04016217; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016776733.1; XM_016921244.1.
DR AlphaFoldDB; A0A2I3RUI9; -.
DR Ensembl; ENSPTRT00000089092.1; ENSPTRP00000068381.1; ENSPTRG00000044235.1.
DR GeneID; 451323; -.
DR CTD; 83786; -.
DR GeneTree; ENSGT00530000063721; -.
DR OrthoDB; 2879691at2759; -.
DR Proteomes; UP000002277; Chromosome 11.
DR Bgee; ENSPTRG00000044235; Expressed in liver and 21 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR13283:SF13; FERM DOMAIN-CONTAINING PROTEIN 8; 1.
DR PANTHER; PTHR13283; KREV INTERACTION TRAPPED 1-RELATED; 1.
DR Pfam; PF00373; FERM_M; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 1..320
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..352
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 322..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 408 AA; 45099 MW; 2DF342A223766202 CRC64;
MDGTEGSAGQ PGPAERSHRS SVSSVGAREV QLKPKHQPYK LGRQWPELLL RFTSAPDDDV
AMDEPFLQFR RNVFFPKRRE LQIHDEEVLR LLYEEAKGNV LAARYPCDVE DCEALGALVC
RVQLGPYQPG HPAACDLREK LDSFLPAHLC KRGQSLFAAL RGRGARAGPG EQGLLNAYRQ
VQEVSSDGGC EAALGTHYRA YLLKCHELPF YGCAFFHGEV DKPAQGFLHR GGRKPVSVAI
SLEGVHVIDS REKHVLLGLR FQELSWDHTS PEEEEPILWL EFDGDSEGTP VNKLLKIYSK
QAELMSSLIE YCIELSQAAE PAGPQDSATG SPSDPSSSPA PVQRPKLRRQ GSVVSSRIQH
LSTIDYVEDG KGIRRVKPKR TTSFFSRQLS LGQGSYTVVQ PGDSLEQG
//
