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Database: UniProt
Entry: A0A2I3RVD0_PANTR
LinkDB: A0A2I3RVD0_PANTR
Original site: A0A2I3RVD0_PANTR 
ID   A0A2I3RVD0_PANTR        Unreviewed;       644 AA.
AC   A0A2I3RVD0; A0A2J8N5L0;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   05-JUN-2019, entry version 8.
DE   SubName: Full=RAPH1 isoform 5 {ECO:0000313|EMBL:PNI67052.1};
DE   SubName: Full=Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 {ECO:0000313|Ensembl:ENSPTRP00000068586};
GN   Name=RAPH1 {ECO:0000313|Ensembl:ENSPTRP00000068586,
GN   ECO:0000313|VGNC:VGNC:14348};
GN   ORFNames=CK820_G0014902 {ECO:0000313|EMBL:PNI67052.1};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000068586, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000068586, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the
RT   human genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|EMBL:PNI67052.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yerkes chimp pedigree #C0471 {ECO:0000313|EMBL:PNI67052.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:PNI67052.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R.,
RA   Chaisson M., Hoppe E., Hill C., Pang A., Hillier L., Baker C.,
RA   Armstrong J., Shendure J., Paten B., Wilson R., Chao H., Schneider V.,
RA   Ventura M., Kronenberg Z., Murali S., Gordon D., Cantsilieris S.,
RA   Munson K., Nelson B., Raja A., Underwood J., Diekhans M., Fiddes I.,
RA   Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPTRP00000068586}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; AACZ04056494; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; NBAG03000236; PNI67052.1; -; Genomic_DNA.
DR   RefSeq; XP_016805845.1; XM_016950356.1.
DR   Ensembl; ENSPTRT00000087054; ENSPTRP00000068586; ENSPTRG00000012831.
DR   GeneID; 459893; -.
DR   CTD; 65059; -.
DR   VGNC; VGNC:14348; RAPH1.
DR   GeneTree; ENSGT00940000156552; -.
DR   OrthoDB; 786893at2759; -.
DR   Proteomes; UP000002277; Chromosome 2B.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   CDD; cd01259; PH_APBB1IP; 1.
DR   Gene3D; 2.30.29.30; -; 1.
DR   InterPro; IPR039664; GRB/APBB1IP.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR039665; PH_APBB1IP.
DR   InterPro; IPR001849; PH_domain.
DR   InterPro; IPR000159; RA_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR11243; PTHR11243; 1.
DR   Pfam; PF00169; PH; 1.
DR   Pfam; PF00788; RA; 1.
DR   SMART; SM00233; PH; 1.
DR   SMART; SM00314; RA; 1.
DR   SUPFAM; SSF54236; SSF54236; 1.
DR   PROSITE; PS50003; PH_DOMAIN; 1.
DR   PROSITE; PS50200; RA; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT   DOMAIN      321    407       Ras-associating. {ECO:0000259|PROSITE:
FT                                PS50200}.
FT   DOMAIN      448    557       PH. {ECO:0000259|PROSITE:PS50003}.
FT   REGION        1     26       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2I3RVD0}.
FT   REGION      179    217       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2I3RVD0}.
FT   REGION      587    622       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2I3RVD0}.
FT   COILED      153    173       {ECO:0000256|SAM:Coils}.
FT   COMPBIAS      7     21       Acidic. {ECO:0000256|MobiDB-lite:
FT                                A0A2I3RVD0}.
SQ   SEQUENCE   644 AA;  72902 MW;  9E12DF8AF188FAA7 CRC64;
     MEQLSDEEID HGAEEDSDKE DQDLDKMFGA WLGELDKLTQ SLDSDKPMEP VKRSPLRQET
     NMANFSYRFS IYNLNEALNH GETVDLDALM ADLCSIEQEL SSIGSGNSKR QITETKATQK
     LPVSRHTLKH GTLKGLSSSS NRIAKPSHAS YSLDDVTAQL EQASLSMDEA AQQSVLEDTK
     PLVTNQHRRT ASAGTVSDAE VHSISNSSRS SITSAASSMD SLDIDKVTRP QELDLTHQGQ
     PITEHAISLR CSSKQAKRHI DFTEEQAELT PHSYLDRETS LLLRNIAGKP SHLLTKEEQA
     AKLKAEKIRV ALEKIKEAQV KKLVIRVHMS DDSSKTMMVD ERQTVRQVLD NLMDKSHCGY
     SLDWSLVETV SELQMERIFE DHENLVENLL NWTRDSQNKL IFMERIEKYA LFKNPQNYLL
     GKKETAEMAD RNKEVLLEEC FCGSSVTVPE IEGVLWLKDD GKKSWKKRYF LLRASGIYYV
     PKGKAKVSRD LVCFLQLDHV NVYYGQDYRN KYKAPTDYCL VLKHPQIQKK SQYIKYLCCD
     DVRTLHQWVN GIRIAKYGKQ LYMNYQEALK RTESAYDWTS LSSSSIKSGS SSSSIPESQS
     NHSNQSDSGV SDTQPAGHVR SQSIVSSVFS EAWKRGTQLE ESSK
//
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