ID A0A2I3S766_PANTR Unreviewed; 598 AA.
AC A0A2I3S766; A0A2J8NIS4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=FCH and double SH3 domains 1 {ECO:0000313|Ensembl:ENSPTRP00000072889.1};
GN Name=FCHSD1 {ECO:0000313|Ensembl:ENSPTRP00000072889.1,
GN ECO:0000313|VGNC:VGNC:6873};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000072889.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000072889.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000072889.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04059174; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3S766; -.
DR Ensembl; ENSPTRT00000081817.1; ENSPTRP00000072889.1; ENSPTRG00000023689.5.
DR VGNC; VGNC:6873; FCHSD1.
DR GeneTree; ENSGT00510000046732; -.
DR Proteomes; UP000002277; Chromosome 5.
DR Bgee; ENSPTRG00000023689; Expressed in lymph node and 21 other cell types or tissues.
DR CDD; cd07678; F-BAR_FCHSD1; 1.
DR CDD; cd11895; SH3_FCHSD1_2; 1.
DR CDD; cd11761; SH3_FCHSD_1; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 2.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR035460; FCHSD_SH3_1.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR15735:SF4; F-BAR AND DOUBLE SH3 DOMAINS PROTEIN 1; 1.
DR PANTHER; PTHR15735; FCH AND DOUBLE SH3 DOMAINS PROTEIN; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00018; SH3_1; 1.
DR Pfam; PF14604; SH3_9; 1.
DR SMART; SM00055; FCH; 1.
DR SMART; SM00326; SH3; 2.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF50044; SH3-domain; 2.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50002; SH3; 2.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077};
KW Lipid-binding {ECO:0000256|ARBA:ARBA00023121};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 12..280
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT DOMAIN 394..455
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 472..535
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT REGION 341..371
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 535..572
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 341..365
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..569
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 598 AA; 66614 MW; 60CCA8F78773AA92 CRC64;
MQPPPRKVKP AQEVKLRFLE QLSILQTWQQ READLLEDIR SYSKQRAAIE REYGQALQKL
AGPFLKREGH RSGEMDSRTV FGAWRCLLDA TVAGGQTRLQ ASDRYRDLAG GTGRSAKEQV
LRKGTENLQR AQAEVLQSVR ELSRSRKLYG QRERVWALAQ EKAADVQARL NRSDHGIFHS
RTSLQKLSTK LSAQSAQYSQ QLQAARNEYL LNLVATNAHL DHYYQEELPA LLKALVSELS
EHLRDPLTSL SRTELEAAEV ILEHAHRGEQ TTSQVSWEQD LKLFLQEPGV FSPTPPQQFQ
PAGTDQVCVL EWGAEGVAGK SGLEKEVQRL TSRAARDYKI QNHGHRERRL SEARLSQRDL
SPTAEDAELS DFEECEETGE LFEEPAPQAL ATRALPCPAH VVFHYQAGRE DELTITEGEW
LEVIEEGDAD EWVKARNQHG EVGFVPERYL NFPDLSLPES SQDSDNPCGA EPTAFLAQAL
YSYTGQSAEE LSFPEGALIR LLPRAQDGVD DGFWRGEFGG RVGVFPSLLV EELLGPPGPP
ELSDPEQMLP SPSPPSFSPP APTSVLDGPP APVLPGDSGG TCACLSYGYI AYWWRLGF
//
