ID A0A2I3SAL9_PANTR Unreviewed; 715 AA.
AC A0A2I3SAL9;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=Terminal nucleotidyltransferase 4A {ECO:0000313|Ensembl:ENSPTRP00000074030.1};
GN Name=TENT4A {ECO:0000313|Ensembl:ENSPTRP00000074030.1,
GN ECO:0000313|VGNC:VGNC:13560};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000074030.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000074030.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000074030.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04025698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3SAL9; -.
DR Ensembl; ENSPTRT00000094963.1; ENSPTRP00000074030.1; ENSPTRG00000016717.6.
DR VGNC; VGNC:13560; TENT4A.
DR GeneTree; ENSGT00940000157811; -.
DR OMA; KWGSRVH; -.
DR Proteomes; UP000002277; Chromosome 5.
DR Bgee; ENSPTRG00000016717; Expressed in cerebellar cortex and 20 other cell types or tissues.
DR GO; GO:1990817; F:poly(A) RNA polymerase activity; IEA:InterPro.
DR GO; GO:0031123; P:RNA 3'-end processing; IEA:UniProt.
DR CDD; cd05402; NT_PAP_TUTase; 1.
DR Gene3D; 1.10.1410.10; -; 1.
DR Gene3D; 3.30.460.10; Beta Polymerase, domain 2; 1.
DR InterPro; IPR043519; NT_sf.
DR InterPro; IPR002058; PAP_assoc.
DR InterPro; IPR002934; Polymerase_NTP_transf_dom.
DR InterPro; IPR045862; Trf4-like.
DR PANTHER; PTHR23092; POLY(A) RNA POLYMERASE; 1.
DR PANTHER; PTHR23092:SF24; TERMINAL NUCLEOTIDYLTRANSFERASE 4A; 1.
DR Pfam; PF01909; NTP_transf_2; 1.
DR Pfam; PF03828; PAP_assoc; 1.
DR SUPFAM; SSF81301; Nucleotidyltransferase; 1.
DR SUPFAM; SSF81631; PAP/OAS1 substrate-binding domain; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 197..305
FT /note="Polymerase nucleotidyl transferase"
FT /evidence="ECO:0000259|Pfam:PF01909"
FT DOMAIN 360..419
FT /note="PAP-associated"
FT /evidence="ECO:0000259|Pfam:PF03828"
FT REGION 1..123
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 533..555
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 659..715
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 36..71
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 715 AA; 77437 MW; AB3A8BD6707B3C87 CRC64;
QPEQKGPANA LWMQIWETSQ GVGRGGSGFG ARRLHKSPSL SSSSSSSSSN AESGTESPGC
SSSSSSSASL GRPGGGRGGA FFNFADGAPS APGTANGHAG PRGPAPAGSP SQHQFHPGRR
KRENKASTYG LNYLLSGSRA AALSGGGGPG AQAPRPGTPW KSRAYSPGIQ GLHEEIIDFY
NFMSPCPEEA AMRREVVKRI ETVVKDLWPT ADVQIFGSFS TGLYLPTSDI DLVVFGKWER
PPLQLLEQAL RKHNVAEPCS IKVLDKATVP IIKLTDQETE VKVDISFNME TGVRAAEFIK
NYMKKYSLLP YLILVLKQFL LQRDLNEVFT GGISSYSLIL MAISFLQLHP RIDARRADEN
LGMLLVEFFE LYGRNFNYLK TGIRIKEGGA YIAKEEIMKA MTSGYRPSML CIEDPLLPGN
DVGRSSYGAM QVKQVFDYAY IVLSHAVSPL ARSYPNRDAE STLGRIIKVT QEVIDYRRWI
KEKWGSKAHP SPGMDSRIKI KERIATCNGE QTQNREPESP YGQRLTLSLS SPQLLSSGSS
ASSDSDTPPC TTPSVYQFSL QAPAPLMAGL PTALPMPSGK PQPTTSRTLI MTTNNQTRFT
IPPPTLGVAP VPCRQAGVEG TASLKAVHHM SSPAIPSASP NPLSSPHLYH KQHNGMKLSM
KGSHGHTQGG GYSSVGSGGV RPPVGNRGHH QYNRTGWRRK KHTHTRDSLP VSLSR
//
