ID A0A2I3SJJ5_PANTR Unreviewed; 492 AA.
AC A0A2I3SJJ5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Microtubule-associated protein {ECO:0000256|RuleBase:RU000686};
GN Name=MAP2 {ECO:0000313|Ensembl:ENSPTRP00000077173.1,
GN ECO:0000313|VGNC:VGNC:1994};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000077173.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000077173.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000077173.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|RuleBase:RU000686}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AACZ04056531; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3SJJ5; -.
DR Ensembl; ENSPTRT00000083192.1; ENSPTRP00000077173.1; ENSPTRG00000012869.7.
DR VGNC; VGNC:1994; MAP2.
DR GeneTree; ENSGT00940000156597; -.
DR Proteomes; UP000002277; Chromosome 2B.
DR Bgee; ENSPTRG00000012869; Expressed in temporal lobe and 19 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR InterPro; IPR027324; MAP2/MAP4/Tau.
DR InterPro; IPR001084; MAP_tubulin-bd_rpt.
DR InterPro; IPR018459; RII-bd_1.
DR PANTHER; PTHR11501; MICROTUBULE-ASSOCIATED PROTEIN; 1.
DR PANTHER; PTHR11501:SF15; MICROTUBULE-ASSOCIATED PROTEIN 2; 1.
DR Pfam; PF10522; RII_binding_1; 1.
DR Pfam; PF00418; Tubulin-binding; 4.
DR PROSITE; PS00229; TAU_MAP_1; 2.
DR PROSITE; PS51491; TAU_MAP_2; 4.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU000686};
KW Cytoskeleton {ECO:0000256|RuleBase:RU000686};
KW Microtubule {ECO:0000256|RuleBase:RU000686};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 85..103
FT /note="RII binding"
FT /evidence="ECO:0000259|Pfam:PF10522"
FT REGION 1..87
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 109..270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 62..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..175
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 193..210
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..252
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..466
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 492 AA; 52212 MW; 35482ACA88AFCD81 CRC64;
MADERKDEAK APHWTSAPLT EASAHSHPPE IKDQGGAGEG LVRSANGFPY REDEEGAFGE
HGSQGTYSNT KENGINGELT SADRETAEEV SARIVQVVTA EAVAVLKGEQ EKEAQHKDQT
AALPLAAEET ANLPPSPPPS PASEQTVTVE EEPNVLFVFS NQDGVTKSPE KRSSLPRPSS
ILPPRRGVSG DRDENSFSLN SSISSSARRT TRSEPIRRAG KSGTSTPTTP GSTAITPGTP
PSYSSRTPGT PGTPSYPRTP HTPGTPKSAI LVPSEKKVAI IRTPPKSPAT PKQLRLINQP
LPDLKNVKSK IGSTDNIKYQ PKGGQVRILN KKIDFSKVQS RCGSKDNIKH SAGGGNVQIV
TKKIDLSHVT SKCGSLKNIR HRPGGGRVKI ESVKLDFKEK AQAKVGSLDN AHHVPGGGNV
KIDSQKLNFR EHAKARVDHG AEIITQSPGR SSVASPRRLS NVSSSGSINL LESPQLATLA
EDVTAALAKQ GL
//
