ID A0A2I3SL42_PANTR Unreviewed; 1611 AA.
AC A0A2I3SL42; A0A2J8PSK2;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=NHS like 1 {ECO:0000313|Ensembl:ENSPTRP00000077727.1};
GN Name=NHSL1 {ECO:0000313|Ensembl:ENSPTRP00000077727.1,
GN ECO:0000313|VGNC:VGNC:3590};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000077727.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000077727.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000077727.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04054445; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04054446; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04054447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_527516.4; XM_527516.5.
DR STRING; 9598.ENSPTRP00000083714; -.
DR Ensembl; ENSPTRT00000088859.1; ENSPTRP00000077727.1; ENSPTRG00000018652.7.
DR GeneID; 472137; -.
DR CTD; 57224; -.
DR VGNC; VGNC:3590; NHSL1.
DR GeneTree; ENSGT00950000182963; -.
DR OrthoDB; 5355272at2759; -.
DR Proteomes; UP000002277; Chromosome 6.
DR Bgee; ENSPTRG00000018652; Expressed in liver and 18 other cell types or tissues.
DR InterPro; IPR024845; NHS-like.
DR PANTHER; PTHR23039; NANCE-HORAN SYNDROME PROTEIN; 1.
DR PANTHER; PTHR23039:SF3; NHS-LIKE PROTEIN 1; 1.
DR Pfam; PF15273; NHS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 433..456
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 531..602
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 647..693
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 715..778
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 791..982
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 998..1536
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1567..1611
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 539..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 577..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 647..665
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..730
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 737..778
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 800..814
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 846..868
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 894..920
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 928..982
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 998..1036
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1041..1062
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1094..1108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1119..1156
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1186..1206
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1248..1262
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1310..1335
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1340..1386
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1399..1426
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1461..1478
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1500..1530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1611 AA; 170780 MW; 0E2A0404F7EBE8B3 CRC64;
MKKEGSSGSF RLQPNTGSLS RAVSWINFSS LSRQTKRLFR SDGELSVCGQ QVEVDDENWI
YRAQPRKAVS NLDEESRWTV HYTAPWHQQE NVFLPTTRPP CVEDLHRQAK LNLKSVLREC
DKLRHDGYRS SQYYSQGPTF AANASPFCDV YQDEDEETDQ KCSLSSSEEE RFISIRRPKT
PTSSDFSDLN TQTNWTKSLP LPTPEEKMRQ QAQTVQADVV PINITASGTG QDDVDGHSVY
TPDHYSTLGR FDSCRSAGQR SETRDSSCQT EDVKVVPPSM RRIRAQKGQG IAAQMGHFSG
SSGNMSVLSD SAGIVFPSRL DSDAGFHSLP RSGARANIQS LEPRLGALGP AGDMNGTFLY
QRGHPQADEN LGHLGGASGT GTLLRPKSQE LRHFESENVM SPACVVSPHA TYSTSIIPNA
TLSSSSEVIA IPTAQSAGQR ESKSSGSSHA RRKSRDHLIS RHAVKGDHQS PGCHWNEGHT
TILSQDLDPH SPGEPTLLSL CDSAVSLNAP ANRENGSQAM PYNCRNNLAF PAHPQDVDGK
SESSYSGGGG HSSSEPWEYK SSGNGRASPL KPHLATPGYS TPTSNMSSCS LDQTSNKEDA
GSLYSEDHDG YCASVHTDSG HGSGNLCNSS DGFGNPRHSV INVFVGRAQK NQGDRSNYQD
KSLSRNISLK KAKKPPLPPS RTDSLRRIPK KSSQCNGQVL NESLIATLQH SLQLSLPGKS
GSSPSQSPCS DLEEPWLPRS RSQSTVSAGS SMTSATTPNV YSLCGATPSQ SDTSSVKSEY
TDPWGYYIDY TGMQEDPGNP AGGCSTSSGV PTGNGPVRHV QEGSRATMPQ VPGGSVKPKI
TSPEKSHRVI SPSSGYSSQS NTPTALTPVP VFLKSMSPAN GKGKPKPKVP ERKSSLISSV
SISSSSTSLS SSTSTEGSGT MKKLDPAVGS PPAPPPPPPV PSPPFPCPAD RSPFLPPPPP
VTDCSQGSPL PHSPVFPPPP PEALIPFCSP PDWCLSPPRP ALSPILPDSP VSLPLPPPLL
PSSEPPPAPP LDPKFMKDTR PPFTNSGQPE SSRGSLRPPS TKEETSRPPM PLITTEALQM
VQLRPVRKNS GAEAAQLSER TAQEQRTPVA PQYHLKPSAF LKSRNSTNEM ESESQPASVT
SSLLTPAKSS SQGDHGSAAE RGGPVSRSPG APSAGEAEAR PSPSTTPLPD SSPSRKPPPI
SKKPKLFLVV PPPQKDFAVE PAENVNKALQ AVPSPTTGEE GSVHSREAKE SSAAQAGSHA
THPGTSVLEG GAAGSMSPGR VEANVPMVQP DVSPAPKQEE PAENSADTGG DGESCLSQQD
GAAGVPETNA AGSSSEACDF LKEDGSDEVM TPSRPRTTED LFAAIHRSKR KVLGRRDSDD
DHSRNHSPSP PVTPTGAAPS LASPKQVGSI QRSIRKSSTS SDNFKALLLK KGSRSDTSAR
MSAAEMLKNT DPRFQRSRSE PSPDAPESPS SCSPSKNRRA QEEWAKNEGL MPRSLSFSGP
RYGRSRTPPS AASSRYSMRN RIQSSPMTVI SEGEGEAVEP VDSIACGALG AAEGCSLDGL
AREEMDEGGL LCGEGPAASL QPQAPGPVDG TASAEGREPS PQCGGSLSEE S
//
