ID A0A2I3STX4_PANTR Unreviewed; 657 AA.
AC A0A2I3STX4; A0A2J8L263;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Vitrin {ECO:0000313|Ensembl:ENSPTRP00000080427.1};
GN Name=VIT {ECO:0000313|Ensembl:ENSPTRP00000080427.1,
GN ECO:0000313|VGNC:VGNC:10808};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000080427.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000080427.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000080427.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04001994; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3STX4; -.
DR Ensembl; ENSPTRT00000096943.1; ENSPTRP00000080427.1; ENSPTRG00000030515.4.
DR VGNC; VGNC:10808; VIT.
DR GeneTree; ENSGT00940000159330; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000030515; Expressed in fibroblast and 9 other cell types or tissues.
DR CDD; cd01472; vWA_collagen; 1.
DR Gene3D; 2.170.130.20; LCCL-like domain; 1.
DR Gene3D; 3.40.50.410; von Willebrand factor, type A domain; 2.
DR InterPro; IPR004043; LCCL.
DR InterPro; IPR036609; LCCL_sf.
DR InterPro; IPR002035; VWF_A.
DR InterPro; IPR036465; vWFA_dom_sf.
DR PANTHER; PTHR24020; COLLAGEN ALPHA; 1.
DR PANTHER; PTHR24020:SF23; VITRIN; 1.
DR Pfam; PF03815; LCCL; 1.
DR Pfam; PF00092; VWA; 2.
DR PRINTS; PR00453; VWFADOMAIN.
DR SMART; SM00603; LCCL; 1.
DR SMART; SM00327; VWA; 2.
DR SUPFAM; SSF69848; LCCL domain; 1.
DR SUPFAM; SSF53300; vWA-like; 2.
DR PROSITE; PS50820; LCCL; 1.
DR PROSITE; PS50234; VWFA; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..26
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 27..657
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015081706"
FT DOMAIN 40..133
FT /note="LCCL"
FT /evidence="ECO:0000259|PROSITE:PS50820"
FT DOMAIN 272..457
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT DOMAIN 474..647
FT /note="VWFA"
FT /evidence="ECO:0000259|PROSITE:PS50234"
FT REGION 150..177
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 199..259
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 150..164
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 199..254
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 71664 MW; DC0CC534EE897D1A CRC64;
MRTVVLTMKA SVIEMFLVLL LTGVHSNKET AKKIKRPKFT VPQINCDVKA GKIINPEFIV
KCPAGCQDPK YHVYGTDVYA SYSSVCGAAV HSGVLDNSGG KILVRKVAGQ SGYKGSYSNG
VQSLSLPRWR ESFIVLESKP KKGVTYPSAL TYSSSKSPAA QAGETTKAYQ RPPIPGTTAQ
PVTLMQLLAV TVAVATPTTL PRPSPSAAST TSIPRPQSVG HRSQEMDLWS TATYTSSQNR
PGADPGTQRQ DPSGAAFQKP VGADVSLDCK IDLSFLIDGS TSIGKRRFRI QKQLLADVAQ
ALDIGPAGPL MGVVQYGDNP ATHFNLKTHT NSRDLKTAIE KITQRGGLSN VGRAISFVTK
NFFSKANGNR SGAPNVVVVL VDGWPTDKVE EASRLARESG INIFFITIEG AAENEKQYVV
EPNFANKAVC RTNGFYSLHV QSWFGLHKTL QPLVKRVCDT DRLACSKTCL NSADIGFVID
GSSSVGTGNF RTVLQFVTNL TKEFEISDTD TRIGAVQYTY EQRLEFGFDK YSSKPDILNA
IKRVGYWSGG TSTGAAINFA LEQLFKKSKP NKRKLMILIT DGRSYDDVRI PAMAAHLKGV
ITYAIGVAWA AQEELEVIAT HPARDHSFFV DEFDNLYQYV PRIIQNICTE FNSQPRN
//
