ID   A0A2I3SUW1_PANTR        Unreviewed;      1046 AA.
AC   A0A2I3SUW1;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Erythrocyte membrane protein band 4.1 like 3 {ECO:0000313|Ensembl:ENSPTRP00000080752.1};
GN   Name=EPB41L3 {ECO:0000313|Ensembl:ENSPTRP00000080752.1,
GN   ECO:0000313|VGNC:VGNC:9911};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000080752.1, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000080752.1, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000080752.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AACZ04065232; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3SUW1; -.
DR   Ensembl; ENSPTRT00000105279.1; ENSPTRP00000080752.1; ENSPTRG00000009844.6.
DR   VGNC; VGNC:9911; EPB41L3.
DR   GeneTree; ENSGT00940000157047; -.
DR   Proteomes; UP000002277; Chromosome 18.
DR   Bgee; ENSPTRG00000009844; Expressed in primary visual cortex and 21 other cell types or tissues.
DR   GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR   GO; GO:0003779; F:actin binding; IEA:InterPro.
DR   GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR   GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR   CDD; cd13184; FERM_C_4_1_family; 1.
DR   Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR   InterPro; IPR008379; Band_4.1_C.
DR   InterPro; IPR014847; FA.
DR   InterPro; IPR000299; FERM_domain.
DR   InterPro; IPR018979; FERM_N.
DR   InterPro; IPR018980; FERM_PH-like_C.
DR   InterPro; IPR011993; PH-like_dom_sf.
DR   InterPro; IPR007477; SAB_dom.
DR   InterPro; IPR029071; Ubiquitin-like_domsf.
DR   PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR   PANTHER; PTHR23280:SF20; BAND 4.1-LIKE PROTEIN 3; 1.
DR   Pfam; PF05902; 4_1_CTD; 1.
DR   Pfam; PF08736; FA; 1.
DR   Pfam; PF09380; FERM_C; 1.
DR   Pfam; PF09379; FERM_N; 1.
DR   Pfam; PF04382; SAB; 1.
DR   PIRSF; PIRSF002304; Membrane_skeletal_4_1; 3.
DR   SMART; SM01195; FA; 1.
DR   SMART; SM01196; FERM_C; 1.
DR   SUPFAM; SSF50729; PH domain-like; 1.
DR   SUPFAM; SSF54236; Ubiquitin-like; 1.
DR   PROSITE; PS50057; FERM_3; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT   DOMAIN          1..249
FT                   /note="FERM"
FT                   /evidence="ECO:0000259|PROSITE:PS50057"
FT   REGION          1..69
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          81..100
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          337..404
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          654..675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        346..389
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1046 AA;  116163 MW;  62D6E5FFA5D42A30 CRC64;
     MTTESGSDSE SKPDQEAEPQ EAAGAQGRAG APVPEPPNEE QQQALEQFAA AAAHSTPVRR
     EVSDKEQEFA ARAAKQLEYQ QLEDDKLSQK SSSSKLSRSP LKIVKKPKSM QCKVILLDGS
     EYTCDVEKRS RGQVLFDKVC EHLNLLEKDY FGLTYRDAEN QKDSEGVEIM LGVCASGLLI
     YRDRLRINRF AWPKVLKISY KRNNFYIKIR PGEFEQFEST IGFKLPNHRA AKRLWKVCVE
     HHTFFRLLLP EAPPKKFLTL GSKFRYSGRT QAQTRRASAL IDRPAPYFER SSSKRYTMSR
     SLDGASVNEN HEIYMKDSMS AAEVGTGQYA TTKGISQTNL ITTVTPEKKA EEERDEEEDK
     RRKGEEVTPV SAIRHEGKTD SERTDTAADG ETTATESDQE EDAELKAQEL EKTQDDLMKH
     QTNISELKRT FLETSTDTAV TNEWEKRLST SPVRLAARQE DAPMIEPLVP EETKEETEIS
     EKVIFLQQGS APFLESQGTE DWVIVDKIPT EVVDGDLKKI VTYKVVTVSS RTGDLPADML
     KSGTIKMQSF EDLAREMQLK EDSKQKIYTL GKSYDTVSGR IVTMTGKAKE GEKVEQPSTT
     EALQKMEKEM PESMKIIPGL AEYEVLETLA DEKSKRGPEV QTTKRKLSES LAAIKEAESR
     RQSPEEDDLK KAPQLEKDVA VLPGLEGRRF SKTEQVPESE VLKVGLFGPR RKSLSEWRYS
     QEPAFTVATA HYVTESSASR VVTKQSSGEK LMDGSEIFSL LESARKPTEF IGGVTSASQS
     WVQKMETKTE SSGIETEPTV HHLPLSTEKV MQETVLVEEQ RVVHASGDAS YSAGESGDAA
     AQPAFTGIKG KEGSALTEEA KEEGGEEVAK AVLEQEETAA ASRERQEEQS AAIHISETLE
     QKPHFESSTV KTETISFGSV SPGGVKLEIS TKEVPVVHTE TKTITYESSQ VDPGTDLEPG
     VLMSAQTITS ETTSTTTTTH ITKTVKGGIS ETRIEKRIVI TGDADIDHDQ ALAQAIKEAK
     EQHPDMSVTK VVVHKETEIT PEDGED
//