ID A0A2I3SVZ3_PANTR Unreviewed; 1694 AA.
AC A0A2I3SVZ3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Uncharacterized protein {ECO:0000313|Ensembl:ENSPTRP00000081147.1};
GN Name=LOC107968981 {ECO:0000313|Ensembl:ENSPTRP00000081147.1};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000081147.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000081147.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000081147.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC185975; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016786190.1; XM_016930701.1.
DR PaxDb; 9598-ENSPTRP00000015329; -.
DR Ensembl; ENSPTRT00000103716.1; ENSPTRP00000081147.1; ENSPTRG00000009573.7.
DR KEGG; ptr:107968981; -.
DR GeneTree; ENSGT00530000063282; -.
DR InParanoid; A0A2I3SVZ3; -.
DR OrthoDB; 4609371at2759; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000009573; Expressed in Brodmann (1909) area 10 and 21 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR015753; LRRC37.
DR InterPro; IPR032754; LRRC37_N.
DR InterPro; IPR029423; LRRC37AB_C.
DR PANTHER; PTHR23045; LEUCINE-RICH REPEAT-CONTAINING PROTEIN 37A; 1.
DR PANTHER; PTHR23045:SF11; LRRC37AB_C DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF15779; LRRC37; 7.
DR Pfam; PF14914; LRRC37AB_C; 1.
DR SMART; SM00369; LRR_TYP; 4.
DR SUPFAM; SSF52058; L domain-like; 1.
DR PROSITE; PS51450; LRR; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..37
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 38..1694
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5014150575"
FT TRANSMEM 1577..1599
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 252..320
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 373..432
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 491..566
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 561..630
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 631..685
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 690..740
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 739..768
FT /note="Leucine-rich repeat-containing protein 37 N-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF15779"
FT DOMAIN 1463..1607
FT /note="LRRC37A/B like protein 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14914"
FT REGION 53..104
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 129..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..534
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 730..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1183..1225
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1301..1323
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1672..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..69
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 135..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..280
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 310..326
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 356..387
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..449
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 476..522
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..748
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1694 AA; 187508 MW; 385A17C148BEB717 CRC64;
MSSAQCRALA CVMSWLRFWG PWPLLMWQLL WLLVKEAQPL EWVKDPLQLT SNPLGPPEPW
SSHSSHFPRE SPHAPTLPAD PWHFDHLGPS ASSEMPAPPQ ESTENLVPFL DTWDSAGELP
LEPEQFLASQ QDLKDKLSPQ ERLPVSPKKL KKDPAQRWSL AEIIGIIRQL STPQSQKQTL
QHEYSSTDIP YPGSLPPELW VKSDEPPGPS EQVGPSQFHL EPETQNPETL EDIQSSSLQQ
EAPAQLPQLP EEEEPSSMQQ EAPALPPESS MESLTLPNHE VTVQPPGEDQ ADYHSPNITV
KPADVEVTIT SEPANETESS QAQQEAPVRF PEEVEPSATQ QEAPVEPPVP PMEHELSISE
QQQPVQPSES SGEVESSPTQ QETPGQPPEH HEVTVSPPGH HQTRHLDSPS VSVKPPDVQL
TIAAEPSAEV GTSLVHQEAT AQLSGSGNDV EPPAIQHGGP PLLPESSEEA GPLAVQRETS
FQSPEPINNE NPSPTQQEAA AEHPQTAEEG ESSLTHQEAP AQTPEFPNVV VAQPPENSHL
TQATVQPLDL GFTITPESMT EVELSPTLKE TPTQPPKKVV LQLRVYQGVT NPTPGQDQAQ
HPVSPSVTVK LLDLGLTITP EPTTEVGHST PPKRTIVSPK HPEVTLPHPD QVQTQHSHLT
RATVQPLDLG FTITPKSMTE VEPSTALMTT APPPGHPEVT IPPSDKGQAQ HSHLTQATVQ
PLDLELTITT KPTTEVKPSP TTEETSTHPP DLGLAITPEP TTEIGHSTAL EKTTAPHPDQ
LQTLHRKLTE VTGPPTELEP TQDSLVQSES YIQDKALAAP EEHKASTSTS ICELCTCGDE
MLSCIDLNPE QRLRQVPVPE PNTHNGTFTI LNFQGNYISY IDGNVWKAYS WTEKLILREN
YLTELHKDSF EGLLSLQYLD LSCNKIQSIE RHTFEPLPFL KFINLSCNVI TELSFGTFQA
WHGMQFLHKL ILNHNPLTTV EDPYLFKLPA LKYLDMGTTL VPLTTLKNIL MMTVELEKLI
LPSHMACCLC QFKNSIEAVC KTVKLHCNSA CLTNTTHCPE EASVGNPEGA FMKVLQARKN
YASTELIVEP EEPSDSSGIN LSGFGSEQLD TNDESDFIST LSHILPYLSV ANLDVKSLLL
PFIKLPTTGN SLAKIQTVGQ NRQRVNRVLM GPRSIQKRHF KEVGRQSIRR EQGAQASVEN
AAEEKRLRSP APRELEQPHT QQGPEKLVGN AVYTKPSFTQ EHKAAVSVLK PFSKGTPSTS
SPAKALPQVR DISISILESA KARVTNTKTS KPIVHSRKKY RFHKTRSRVT HRTPTVKKSP
KVRKKSYLSR LMLANRLPFS AAKSLINSPS QGAFSSLGDL SPQENPFLEV SAPSEHFIEN
NNTKDTTARN AFGENVFMEN TNMPEGTISE NTNYNHPPEA DSAGTAFNLG PTVKQTETKW
EYNNVGTDLS PEPKSFNYPL LSSPGDQLEI QLTQQLQSLI PNNNVRRLIA HVIRTLKMDC
SGAHVQVTCA KLISRTGHLM KLLSGQQEVK ASKIEWDTDQ WKTENYINES TEAQSEQKEK
SLELTKEVPG YGYTTKLIVA LIVTGILMIL IILFCLIVIC CHRRSLQEDE EGFSRGIFRF
LPGRRCSSRR ESQDGLFPFR QPLWLKDMYK PLSATRVNNH AWKLHKKSSN EDEILLNRDP
GDSEAPTEKE EEES
//
