GenomeNet

Database: UniProt
Entry: A0A2I3SW58_PANTR
LinkDB: A0A2I3SW58_PANTR
Original site: A0A2I3SW58_PANTR 
ID   A0A2I3SW58_PANTR        Unreviewed;       911 AA.
AC   A0A2I3SW58;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   10-APR-2019, entry version 7.
DE   SubName: Full=NLR family pyrin domain containing 3 {ECO:0000313|Ensembl:ENSPTRP00000081238};
GN   Name=NLRP3 {ECO:0000313|VGNC:VGNC:11565};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000081238, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000081238, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the
RT   human genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000081238}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; AACZ04033613; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPTRT00000081977; ENSPTRP00000081238; ENSPTRG00000002198.
DR   VGNC; VGNC:11565; NLRP3.
DR   GeneTree; ENSGT00940000162415; -.
DR   Proteomes; UP000002277; Chromosome 1.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.80.10.10; -; 1.
DR   InterPro; IPR004020; DAPIN.
DR   InterPro; IPR011029; DEATH-like_dom_sf.
DR   InterPro; IPR001611; Leu-rich_rpt.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR029495; NACHT-assoc.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR041267; NLRC_HD2.
DR   InterPro; IPR041075; NOD2_WH.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF14484; FISNA; 1.
DR   Pfam; PF13516; LRR_6; 3.
DR   Pfam; PF05729; NACHT; 1.
DR   Pfam; PF17776; NLRC4_HD2; 1.
DR   Pfam; PF17779; NOD2_WH; 1.
DR   Pfam; PF02758; PYRIN; 1.
DR   SMART; SM01288; FISNA; 1.
DR   SMART; SM01289; PYRIN; 1.
DR   SUPFAM; SSF47986; SSF47986; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50824; DAPIN; 1.
DR   PROSITE; PS50837; NACHT; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|SAAS:SAAS01046498};
KW   Complete proteome {ECO:0000313|Proteomes:UP000002277};
KW   Leucine-rich repeat {ECO:0000256|SAAS:SAAS01143294};
KW   Nucleotide-binding {ECO:0000256|SAAS:SAAS01046502};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Repeat {ECO:0000256|SAAS:SAAS01046485}.
FT   DOMAIN        1     93       Pyrin. {ECO:0000259|PROSITE:PS50824}.
FT   DOMAIN      220    536       NACHT. {ECO:0000259|PROSITE:PS50837}.
SQ   SEQUENCE   911 AA;  104358 MW;  16BE0B94FFDABE3C CRC64;
     MKMASTRCKL ARYLEDLEDV DLKKFKMHLE DYPPQKGCIP LPRGQTEKAD HVDLATLMID
     FNGEEKAWAM AVWIFAAINR RDLYEKAKRD EPKWGSDNAC VSNPTVICQE DSIEEEWMGL
     LEYLSRISIC KMKKDYRKKY RKYVRSRFQC IEDRNARLGE SVSLNKRYTR LRLIKEHRSQ
     QEREQELLAI GKTKACESPV SPIKMEMLFD PDDEHSEPVH TVVFQGAAGI GKTILARKIM
     LDWALGTLYQ DRFDYLFYIH CREVSLVTQR SLGDLIMSCC PDPNPPIHKI VRKPSRILFL
     MDGFDELQGA FDEHIGPLCT DWQKAERGDI LLSSLIRKKL LPEASLLITT RPVALEKLQH
     LLDHPRHVEI LGFSEAKRKE YFFKYFSDEA QARAAFSLIQ QNEVLFTMCF IPLVCWIVCT
     GLKQQMESGK SLAQTSKTTT AVYVFFLSSL LQPRGGSQEH RLCAHLWGLC SLAADGIWNQ
     KILFEESDLR NHGLQKADVS AFLRMNLFQK EVDCEKFYSF IHMTFQEFFA AMYYLLEEEK
     EGRTNVPGSR LKLPSRDVTV LLENYGKFEK GYLIFVVRFL FGLVNQERTS YLEKKLSCKI
     SQQIRLELLK WIEVKAKAKK LQIQPSQLEL FYCLYEMQEE DFVQRAMDYF PKIEINLSTR
     MDHVVSSFCI ENCHRVESLS LGFLHNMPKE EEEEEKEGRH PDMVQCVLPG SSHAACSHGL
     GRCGLSHECC FDISLVLSSN QKLVELDLSD NALSDFGIRL LCVGLKHLLC NLKKLWLVNS
     GLTSVCCSAL SSVLSTNPNL THLYLRGNTL GDKGIKLLCE GLLHPDCKLQ VLELDNCNLT
     SHCCWDLSTL LTSSQSLRKL SLGNNDLGDL GVMMFCEVLK QQSCLLQNLG CPLQPNTLHS
     NRKSPEPAPS S
//
DBGET integrated database retrieval system