ID A0A2I3T0I3_PANTR Unreviewed; 227 AA.
AC A0A2I3T0I3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Ral GTPase activating protein catalytic subunit alpha 2 {ECO:0000313|Ensembl:ENSPTRP00000082363.1};
GN Name=RALGAPA2 {ECO:0000313|Ensembl:ENSPTRP00000082363.1,
GN ECO:0000313|VGNC:VGNC:9946};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000082363.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000082363.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000082363.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04064886; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04064887; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3T0I3; -.
DR Ensembl; ENSPTRT00000095400.1; ENSPTRP00000082363.1; ENSPTRG00000013306.7.
DR VGNC; VGNC:9946; RALGAPA2.
DR GeneTree; ENSGT00950000183139; -.
DR Proteomes; UP000002277; Chromosome 20.
DR Bgee; ENSPTRG00000013306; Expressed in skeletal muscle tissue and 21 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-UniRule.
DR GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR InterPro; IPR035974; Rap/Ran-GAP_sf.
DR InterPro; IPR000331; Rap/Ran_GAP_dom.
DR InterPro; IPR027107; Tuberin/Ral-act_asu.
DR PANTHER; PTHR10063:SF2; RAL GTPASE-ACTIVATING PROTEIN SUBUNIT ALPHA-2; 1.
DR PANTHER; PTHR10063; TUBERIN; 1.
DR Pfam; PF02145; Rap_GAP; 1.
DR SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR PROSITE; PS50085; RAPGAP; 1.
PE 4: Predicted;
KW GTPase activation {ECO:0000256|ARBA:ARBA00022468, ECO:0000256|PROSITE-
KW ProRule:PRU00165}; Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 23..227
FT /note="Rap-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50085"
SQ SEQUENCE 227 AA; 25671 MW; 804F6288DCAFFCC3 CRC64;
MNSWDRRKNF HLLKKNSKLL RELKNLDSRQ CRETHKIAVF YIAEGQEDKC SILSNERGSQ
AYEDFVAGLG WEVDLSTHCG FMGGLQRNGS TGQTAPYYAT STVEVIFHVS TRMPSDSDDS
LTKKLRHLGN DEVHIVWSEH SRDYRRGIIP TAFGDVSIII YPMKNHMFFI AITKKPEVPF
FGPLFDGAIV SGKLLPSLVC ATCINASRAV KCLIPLYQSL YLFALNM
//
