ID A0A2I3T0U5_PANTR Unreviewed; 161 AA.
AC A0A2I3T0U5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=TNF receptor associated factor 4 {ECO:0000313|Ensembl:ENSPTRP00000082866.1};
GN Name=TRAF4 {ECO:0000313|Ensembl:ENSPTRP00000082866.1,
GN ECO:0000313|VGNC:VGNC:9737};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000082866.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000082866.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000082866.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04041502; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3T0U5; -.
DR Ensembl; ENSPTRT00000078534.1; ENSPTRP00000082866.1; ENSPTRG00000008936.7.
DR VGNC; VGNC:9737; TRAF4.
DR GeneTree; ENSGT00940000158628; -.
DR Proteomes; UP000002277; Chromosome 17.
DR Bgee; ENSPTRG00000008936; Expressed in cortex of kidney and 21 other cell types or tissues.
DR GO; GO:0019899; F:enzyme binding; IEA:UniProt.
DR GO; GO:0042802; F:identical protein binding; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0048584; P:positive regulation of response to stimulus; IEA:UniProt.
DR InterPro; IPR002083; MATH/TRAF_dom.
DR InterPro; IPR008974; TRAF-like.
DR InterPro; IPR049342; TRAF_MEP1_MATH_dom.
DR InterPro; IPR018957; Znf_C3HC4_RING-type.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR10131; TNF RECEPTOR ASSOCIATED FACTOR; 1.
DR PANTHER; PTHR10131:SF144; TNF RECEPTOR-ASSOCIATED FACTOR 4; 1.
DR Pfam; PF21355; TRAF-mep_MATH; 1.
DR Pfam; PF00097; zf-C3HC4; 1.
DR SMART; SM00061; MATH; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF49599; TRAF domain-like; 1.
DR PROSITE; PS50144; MATH; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 1..153
FT /note="MATH"
FT /evidence="ECO:0000259|PROSITE:PS50144"
FT DOMAIN 18..46
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
SQ SEQUENCE 161 AA; 18568 MW; 97B8B1B5C7100D1F CRC64;
MPGFDYKFLE KPKRRLLCPL CGKPMREPVQ VSTCGHRFCD TCLQEFLSGE GTHLSLYIRV
LPGAFDNLLE WPFARRVTFS LLDQSDPGLA KPQHVTETFH PDPNWKNFQK PGTWRGSLDE
SSLGFGYPKF ISHQDIRKRN YVRDDAVFIR AAVELPRKIL S
//
