ID A0A2I3T835_PANTR Unreviewed; 93 AA.
AC A0A2I3T835; A0A2J8QU34;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial {ECO:0000256|ARBA:ARBA00014585};
DE AltName: Full=Complex I-AGGG {ECO:0000256|ARBA:ARBA00031368};
DE AltName: Full=NADH-ubiquinone oxidoreductase AGGG subunit {ECO:0000256|ARBA:ARBA00031736};
GN Name=NDUFB2 {ECO:0000313|Ensembl:ENSPTRP00000085411.1,
GN ECO:0000313|VGNC:VGNC:4441};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000085411.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000077857.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000085411.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Accessory subunit of the mitochondrial membrane respiratory
CC chain NADH dehydrogenase (Complex I), that is believed not to be
CC involved in catalysis. Complex I functions in the transfer of electrons
CC from NADH to the respiratory chain. The immediate electron acceptor for
CC the enzyme is believed to be ubiquinone.
CC {ECO:0000256|ARBA:ARBA00003195}.
CC -!- SUBUNIT: Complex I is composed of 45 different subunits.
CC {ECO:0000256|ARBA:ARBA00011533}.
CC -!- SIMILARITY: Belongs to the complex I NDUFB2 subunit family.
CC {ECO:0000256|ARBA:ARBA00005923}.
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DR EMBL; AC220988; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_009452507.1; XM_009454232.1.
DR RefSeq; XP_016800957.1; XM_016945468.1.
DR Ensembl; ENSPTRT00000090226.1; ENSPTRP00000085411.1; ENSPTRG00000047330.1.
DR Ensembl; ENSPTRT00000102695.1; ENSPTRP00000077857.1; ENSPTRG00000019771.6.
DR GeneID; 463780; -.
DR CTD; 4708; -.
DR VGNC; VGNC:4441; NDUFB2.
DR GeneTree; ENSGT00390000004044; -.
DR OrthoDB; 5402335at2759; -.
DR Proteomes; UP000002277; Unplaced.
DR Bgee; ENSPTRG00000019771; Expressed in skeletal muscle tissue and 21 other cell types or tissues.
DR GO; GO:0005747; C:mitochondrial respiratory chain complex I; IEA:InterPro.
DR InterPro; IPR026627; NDUFB2_animal.
DR PANTHER; PTHR15223:SF1; NADH DEHYDROGENASE [UBIQUINONE] 1 BETA SUBCOMPLEX SUBUNIT 2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR15223; NADH-UBIQUINONE OXIDOREDUCTASE AGGG SUBUNIT; 1.
DR Pfam; PF14813; NADH_B2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Transit peptide {ECO:0000256|ARBA:ARBA00022946};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 73..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 93 AA; 11080 MW; 12BC9C8EE0DEE400 CRC64;
MLKNHSGCRE WRRSPRESAV GAGGGVHIEP RYRQFPQLTR SQVFQSEFFS GLMWFWILWR
FWHDSEEVLG HFPYPDPSQW TDEELGIPPD DED
//
