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Database: UniProt
Entry: A0A2I3TCW5_PANTR
LinkDB: A0A2I3TCW5_PANTR
Original site: A0A2I3TCW5_PANTR 
ID   A0A2I3TCW5_PANTR        Unreviewed;      1021 AA.
AC   A0A2I3TCW5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   05-DEC-2018, entry version 4.
DE   SubName: Full=Inositol 1,4,5-trisphosphate receptor type 1 {ECO:0000313|Ensembl:ENSPTRP00000086716};
GN   Name=ITPR1 {ECO:0000313|Ensembl:ENSPTRP00000086716,
GN   ECO:0000313|VGNC:VGNC:7976};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000086716, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000086716, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the
RT   human genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000086716}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; AACZ04000031; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; AACZ04000032; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPTRT00000099996; ENSPTRP00000086716; ENSPTRG00000014570.
DR   VGNC; VGNC:7976; ITPR1.
DR   GeneTree; ENSGT00940000155071; -.
DR   Proteomes; UP000002277; Chromosome 3.
DR   GO; GO:0005783; C:endoplasmic reticulum; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0070679; F:inositol 1,4,5 trisphosphate binding; IEA:InterPro.
DR   GO; GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; IEA:InterPro.
DR   InterPro; IPR014821; Ins145_P3_rcpt.
DR   InterPro; IPR000493; InsP3_rcpt.
DR   InterPro; IPR036300; MIR_dom_sf.
DR   InterPro; IPR016093; MIR_motif.
DR   InterPro; IPR000699; RIH_dom.
DR   InterPro; IPR015925; Ryanodine_recept-rel.
DR   InterPro; IPR035910; RyR/IP3R_RIH_dom_sf.
DR   PANTHER; PTHR13715; PTHR13715; 1.
DR   Pfam; PF08709; Ins145_P3_rec; 1.
DR   Pfam; PF02815; MIR; 1.
DR   Pfam; PF01365; RYDR_ITPR; 1.
DR   PRINTS; PR00779; INSP3RECEPTR.
DR   SMART; SM00472; MIR; 4.
DR   SUPFAM; SSF100909; SSF100909; 1.
DR   SUPFAM; SSF82109; SSF82109; 2.
DR   PROSITE; PS50919; MIR; 5.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002277};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Repeat {ECO:0000256|SAAS:SAAS00903904}.
FT   DOMAIN       54    108       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      115    165       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      173    229       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      236    315       MIR. {ECO:0000259|PROSITE:PS50919}.
FT   DOMAIN      321    377       MIR. {ECO:0000259|PROSITE:PS50919}.
SQ   SEQUENCE   1021 AA;  116445 MW;  AF6E74EE43753ED8 CRC64;
     MLCPMNRYSA QKQFWKAAKP GANSTTDAVL LNKLHHAADL EKKQNETENR KLLGTVIQYG
     NVIQLLHLKS NKYLTVNKRL PALLEKNAMR VTLDEAGNEG SWFYIQPFYK LRSIGDSVVI
     GDKVVLNPVN AGQPLHASSH QLVDNPGCNE VNSVNCNTSW KIVLFMKWSD NKDDILKGGD
     VVRLFHAEQE KFLTCDEHRK KQHVFLRTTG RQSATSATSS KALWEVEVVQ HDPCRGGAGY
     WNSLFRFKHL ATGHYLAAEV DPDFEEECLE FQPSVDPDQD ASRSRLRNAQ EKMVYSLVSV
     PEGNDISSIF ELDPTTLRGG DSLVPRNSYV RLRHLCTNTW VHSTNIPIDK EEEKPVMLKI
     GTSPVKEDKE AFAIVPVSPA EVRDLDFAND ASKVLGSIAG KLEKGTITQN ERRSVTKLLE
     DLVYFVTGGT NSGQDVLEVV FSKPNRERQK LMREQNILKQ IFKLLQAPFT DCGDGPMLRL
     EELGDQRHAP FRHICRLCYR VLRHSQQDYR KNQEYIAKQF GFMQKQIGYD VLAEDTITAL
     LHNNRKLLEK HITAAEIDTF VSLVRKNREP RFLDYLSDLC VSMNKSIPVT QELICKAVLN
     PTNADILIET KLVLSRFEFE GVSSTGENAL EAGEDEEEVW LFWRDSNKEI RSKSVRELAQ
     DAKEGQKEDR DVLSYYRYQL NLFARMCLDR QYLAINEISG QLDVDLILRC MSDENLPYDL
     RASFCRLMLH MHVDRDPQEQ VTPVKYARLW SEIPSEIAID DYDSSGASKD EIKERFAQTM
     EFVEEYLRDV VCQRFPFSDK EKNKLTFEVV NLARNLIYFG FYNFSDLLRL TKILLAILDC
     VHVTTIFPIS KMAKGEENKG SNVMRSIHGV GELMTQVVLR GGGFLPMTPM AAAPEGNVKQ
     AEPEKEDIMV MDTKLKIIEI LQFILNVRLD YRISCLLCIF KREFDESNSQ TSETSSGNSS
     QEGPSNVPGA LDFEHIEEQA EGIFGGRKVY FQLLFCRWFC SWEGCSSRAL RGLPFIMLVN
     I
//
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