ID A0A2I3TIU4_PANTR Unreviewed; 211 AA.
AC A0A2I3TIU4;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Kv channel-interacting protein 4 {ECO:0000256|ARBA:ARBA00040738};
GN Name=KCNIP4 {ECO:0000313|Ensembl:ENSPTRP00000089171.1,
GN ECO:0000313|VGNC:VGNC:48912};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000089171.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000089171.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000089171.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004202};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202}.
CC -!- SIMILARITY: Belongs to the recoverin family.
CC {ECO:0000256|ARBA:ARBA00006049}.
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DR EMBL; AACZ04033692; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033693; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033694; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033695; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033696; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033697; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033698; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033699; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033700; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04033701; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3TIU4; -.
DR Ensembl; ENSPTRT00000100078.1; ENSPTRP00000089171.1; ENSPTRG00000015948.6.
DR VGNC; VGNC:48912; KCNIP4.
DR GeneTree; ENSGT00940000158985; -.
DR OMA; GXDFIKG; -.
DR Proteomes; UP000002277; Chromosome 4.
DR Bgee; ENSPTRG00000015948; Expressed in temporal lobe and 20 other cell types or tissues.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR028846; Recoverin.
DR PANTHER; PTHR23055; CALCIUM BINDING PROTEINS; 1.
DR PANTHER; PTHR23055:SF30; KV CHANNEL-INTERACTING PROTEIN 4; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR PRINTS; PR00450; RECOVERIN.
DR SMART; SM00054; EFh; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR PROSITE; PS00018; EF_HAND_1; 3.
DR PROSITE; PS50222; EF_HAND_2; 3.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 81..116
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 117..152
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 165..200
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
SQ SEQUENCE 211 AA; 24651 MW; 48EE8B7F1ABA1540 CRC64;
MNFRIVFSNS VKNNHDSVED ELEMATVRHR PEALELLEAQ SKFTKKELQI LYRGFKNECP
SGVVNEETFK EIYSQFFPQG DSTTYAHFLF NAFDTDHNGA VSFEDFIKGL SILLRGTVQE
KLNWAFNLYD INKDGYITKE EMLDIMKAIY DMMGKCTYPV LKEDAPRQHV ETFFQKMDKN
KDGVVTIDEF IESCQKDENI MRSMQLFENV I
//
