ID   A0A2I3TKM1_PANTR        Unreviewed;       673 AA.
AC   A0A2I3TKM1; A0A2J8NNF1;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=DNA polymerase kappa {ECO:0000313|Ensembl:ENSPTRP00000089805.1};
GN   Name=POLK {ECO:0000313|Ensembl:ENSPTRP00000089805.1,
GN   ECO:0000313|VGNC:VGNC:8631};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000089805.1, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000089805.1, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000089805.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   EMBL; AACZ04061826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   AlphaFoldDB; A0A2I3TKM1; -.
DR   Ensembl; ENSPTRT00000092676.1; ENSPTRP00000089805.1; ENSPTRG00000016997.6.
DR   VGNC; VGNC:8631; POLK.
DR   GeneTree; ENSGT00940000156667; -.
DR   Proteomes; UP000002277; Chromosome 5.
DR   Bgee; ENSPTRG00000016997; Expressed in lymph node and 21 other cell types or tissues.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.150.810; -; 1.
DR   Gene3D; 3.30.70.270; -; 1.
DR   Gene3D; 3.40.1170.60; -; 1.
DR   Gene3D; 3.30.160.60; Classic Zinc Finger; 2.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR006642; Rad18_UBZ4.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR001126; UmuC.
DR   PANTHER; PTHR11076:SF33; DNA POLYMERASE KAPPA; 1.
DR   PANTHER; PTHR11076; DNA REPAIR POLYMERASE UMUC / TRANSFERASE FAMILY MEMBER; 1.
DR   Pfam; PF00817; IMS; 1.
DR   SMART; SM00734; ZnF_Rad18; 2.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   PROSITE; PS50173; UMUC; 1.
DR   PROSITE; PS51908; ZF_UBZ4; 2.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763, ECO:0000256|PROSITE-
KW   ProRule:PRU01256};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204, ECO:0000256|PROSITE-
KW   ProRule:PRU01256}; Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU01256}.
FT   DOMAIN          103..313
FT                   /note="UmuC"
FT                   /evidence="ECO:0000259|PROSITE:PS50173"
FT   DOMAIN          423..453
FT                   /note="UBZ4-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51908"
FT   DOMAIN          579..609
FT                   /note="UBZ4-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51908"
FT   REGION          619..661
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          57..99
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        623..641
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   673 AA;  76648 MW;  37AEF8298E4EEE75 CRC64;
     MDSTKEKCDS YKDDLLLRMG LNDNKAGMEG LDKEKINKII MEATKGSRFY GNELKKEKQV
     NQRIENMMQQ KAQITSQQLR KAQLQVDRFA MELEQSRNLS NTIVHIDMDA FYAAVEMRDN
     PELKDKPIAV GSMSMLSTSN YHARRFGVRA AMPGFIAKRL CPQLIIVPPN FDKYRAVSKE
     VKEILADYDP NFMAMSLDEA YLNITKHLEE RQNWPEDKRR YFIKMGSSVE NDNPGKEVNK
     LSEHERSISP LLFEESPSDV QPPGDPFQVN FEEQNNPQIL QNSVVFGTSA QEVVKEIRFR
     IEQKTTLTAS AGVRISSFPN EEDRKRQQRS IIGFLQAGNQ ALSATECTLE KTDKDKFVKP
     LEMSHKKSFF DKKRSERKWS HQDTFKCEAV NKQSFQTSQP FQVLKKKINE NLEISENSDD
     CQIFTCPVCF RTQGCISLEA LNKHVDECLD GPSISENFKM FSCSHVSATK VNKKENVPAS
     SLCEKQDYEA HPKIKEISSV DCIALVDTID NSSKAESIDA LSNKHSKEEC SSLPSKYFNI
     EHCHQNSSST VSLENEDVGS LSRQEYRQPY LCEVKTGQAL VCPVCNVEQK TSDLTLFNVH
     VDVCLNKSFI QELRKDKFNP VNQPKESSRS TGSSSGVQKA VTRTKRPGLM TKYSTSKKIK
     PNNPKHTLDI FFK
//