ID A0A2I3TLJ4_PANTR Unreviewed; 137 AA.
AC A0A2I3TLJ4; A0A2J8MJZ5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=WAP four-disulfide core domain 3 {ECO:0000313|Ensembl:ENSPTRP00000090105.1};
GN Name=WFDC3 {ECO:0000313|Ensembl:ENSPTRP00000090105.1,
GN ECO:0000313|VGNC:VGNC:10139};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000090105.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000090105.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000090105.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AACZ04052839; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3TLJ4; -.
DR Ensembl; ENSPTRT00000085076.1; ENSPTRP00000090105.1; ENSPTRG00000013562.6.
DR VGNC; VGNC:10139; WFDC3.
DR GeneTree; ENSGT00730000111454; -.
DR Proteomes; UP000002277; Chromosome 20.
DR Bgee; ENSPTRG00000013562; Expressed in testis and 13 other cell types or tissues.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR Gene3D; 4.10.75.10; Elafin-like; 2.
DR InterPro; IPR036645; Elafin-like_sf.
DR InterPro; IPR008197; WAP_dom.
DR PANTHER; PTHR19441:SF82; WAP FOUR-DISULFIDE CORE DOMAIN PROTEIN 3; 1.
DR PANTHER; PTHR19441; WHEY ACDIC PROTEIN WAP; 1.
DR Pfam; PF00095; WAP; 2.
DR PRINTS; PR00003; 4DISULPHCORE.
DR SMART; SM00217; WAP; 2.
DR SUPFAM; SSF57256; Elafin-like; 2.
DR PROSITE; PS51390; WAP; 2.
PE 4: Predicted;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..137
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015082051"
FT DOMAIN 26..68
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
FT DOMAIN 69..113
FT /note="WAP"
FT /evidence="ECO:0000259|PROSITE:PS51390"
SQ SEQUENCE 137 AA; 14686 MW; DB17D55C5DA78625 CRC64;
MMLSCLFLLK ALLALGSLES WITAGEHAKE GECPPDKNPC KELCQGDELC PAEQKCCTTG
CGRICRDIPK GRGGDCPKVL VGLCIVGCVM DENCQAGEKC CKSGCGRFCV PPVLPPKLTM
NPNWTVRSDS ELEIPVP
//
