ID A0A2I3TMN5_PANTR Unreviewed; 855 AA.
AC A0A2I3TMN5;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=BICD cargo adaptor 2 {ECO:0000313|Ensembl:ENSPTRP00000090169.1};
GN Name=BICD2 {ECO:0000313|Ensembl:ENSPTRP00000090169.1,
GN ECO:0000313|VGNC:VGNC:9214};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000090169.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000090169.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000090169.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the BicD family.
CC {ECO:0000256|ARBA:ARBA00010061}.
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DR EMBL; AACZ04057407; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04057408; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR Ensembl; ENSPTRT00000109371.1; ENSPTRP00000090169.1; ENSPTRG00000021116.6.
DR VGNC; VGNC:9214; BICD2.
DR GeneTree; ENSGT00940000154471; -.
DR InParanoid; A0A2I3TMN5; -.
DR Proteomes; UP000002277; Chromosome 9.
DR Bgee; ENSPTRG00000021116; Expressed in lymph node and 21 other cell types or tissues.
DR GO; GO:0005642; C:annulate lamellae; IEA:Ensembl.
DR GO; GO:0005813; C:centrosome; IEA:Ensembl.
DR GO; GO:0031410; C:cytoplasmic vesicle; IEA:Ensembl.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; IBA:GO_Central.
DR GO; GO:0005643; C:nuclear pore; IEA:Ensembl.
DR GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR GO; GO:0008093; F:cytoskeletal anchor activity; IEA:InterPro.
DR GO; GO:0034452; F:dynactin binding; IBA:GO_Central.
DR GO; GO:0070840; F:dynein complex binding; IBA:GO_Central.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IBA:GO_Central.
DR GO; GO:0031267; F:small GTPase binding; IEA:Ensembl.
DR GO; GO:0051642; P:centrosome localization; IEA:Ensembl.
DR GO; GO:0072393; P:microtubule anchoring at microtubule organizing center; IBA:GO_Central.
DR GO; GO:0007018; P:microtubule-based movement; IBA:GO_Central.
DR GO; GO:0072385; P:minus-end-directed organelle transport along microtubule; IEA:Ensembl.
DR GO; GO:0034067; P:protein localization to Golgi apparatus; IBA:GO_Central.
DR GO; GO:0070507; P:regulation of microtubule cytoskeleton organization; IBA:GO_Central.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR Gene3D; 6.10.250.2470; -; 1.
DR InterPro; IPR018477; BICD.
DR PANTHER; PTHR31233; BICAUDAL D FAMILY MEMBER; 1.
DR PANTHER; PTHR31233:SF7; PROTEIN BICAUDAL D HOMOLOG 2; 1.
DR Pfam; PF09730; BicD; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT REGION 83..103
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 307..332
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 400..425
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 458..477
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 555..622
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 118..260
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 669..788
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 404..425
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 855 AA; 96294 MW; 3746FA09C2B37D29 CRC64;
XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX XXXXXXXXXX
XXXXXXXXXX XXXXXXXXXX AFGQAHTNHK KVAADGESRE ESLIQESASK EQYYVRKVLE
LQTELKQLRN VLTNTQSENE RLASVAQELK EINQNVEIQR GRLRDDIKEY KFREARLLQD
YSELEEENIS LQKQVSVLRQ NQVEFEGLKH EIKRLEEETE YLNSQLEDAI RLKEISERQL
EEALETLKTE REQKNSLRKE LSHYMSINDS FYTSHLHVSL DGLKFSDDAA EPNNDAEALV
NGFEHGGLAK LPLDNKTSTP KKEGLAPPSP SLVSDLLSEL NISEIQKLKQ QLMQMEREKA
GLLATLQDTQ KQLEHTRGSL SEQQEKVTRL TENLSALRRL QASKERQTAL DNEKDRDSHE
DGDYYEVDIN GPEILACKYH VAVAEAGELR EQLKALRSTH EAREAQHAEE KGRYEAEGQA
LTEKVSLLEK ASRQDRELLA RLEKELKKVS DVAGETQGSL SVAQDELVTF SEELANLYHH
VCMCNNETPN RVMLDYYREG QGGAGRTSPG GRTSPEARGR RSPILLPKGL LAPEAGRADG
GTGDSSPSPG SSLPSPLSDP RREPMNIYNL IAIIRDQIKH LQAAVDRTTE LSRQRIASQE
LGPAVDKDKE ALMEEILKLK SLLSTKREQI TTLRTVLKAN KQTAEVALAN LKSKYENEKA
MVTETMMKLR NELKALKEDA ATFSSLRAMF ATRCDEYITQ LDEMQRQLAA AEDEKKTLNS
LLRMAIQQKL ALTQRLELLE LDHEQTRRGR AKAAPKTKPV TPSVSHTCAC ASDRAEGTGL
ANQVFCSEKH SIYCD
//
