ID A0A2I3TN01_PANTR Unreviewed; 522 AA.
AC A0A2I3TN01;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Septin-10 {ECO:0000256|ARBA:ARBA00039309};
GN Name=SEPTIN10 {ECO:0000313|Ensembl:ENSPTRP00000090299.1,
GN ECO:0000313|VGNC:VGNC:58083};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000090299.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000090299.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000090299.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. Septin GTPase family.
CC {ECO:0000256|RuleBase:RU004560}.
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DR EMBL; AACZ04002799; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3TN01; -.
DR Ensembl; ENSPTRT00000094734.1; ENSPTRP00000090299.1; ENSPTRG00000048384.1.
DR VGNC; VGNC:58083; SEPTIN10.
DR GeneTree; ENSGT00940000155238; -.
DR InParanoid; A0A2I3TN01; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000048384; Expressed in fibroblast and 21 other cell types or tissues.
DR GO; GO:0032153; C:cell division site; IBA:GO_Central.
DR GO; GO:0015630; C:microtubule cytoskeleton; IBA:GO_Central.
DR GO; GO:0031105; C:septin complex; IBA:GO_Central.
DR GO; GO:0005940; C:septin ring; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0060090; F:molecular adaptor activity; IBA:GO_Central.
DR GO; GO:0061640; P:cytoskeleton-dependent cytokinesis; IBA:GO_Central.
DR CDD; cd01850; CDC_Septin; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR030379; G_SEPTIN_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016491; Septin.
DR PANTHER; PTHR18884; SEPTIN; 1.
DR PANTHER; PTHR18884:SF50; SEPTIN-10; 1.
DR Pfam; PF00735; Septin; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51719; G_SEPTIN; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134, ECO:0000256|RuleBase:RU004560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU004560};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT DOMAIN 54..320
FT /note="Septin-type G"
FT /evidence="ECO:0000259|PROSITE:PS51719"
FT COILED 358..414
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 522 AA; 60559 MW; 8D45AD06682A6E60 CRC64;
FLFQSHMATK TTCMSSQGSD DEQIKRENIR SLTMSGHVGF ESLPDQLVNR SIQQGFCFNI
LCVGETGIGK STLIDTLFNT NFEDYESSHF CPNVKLKAQT YELQESNVQL KLTIVNTVGF
GDQINKEESY QPIVDYIDAQ FEAYLQEELK IKRSLFTYHD SRIHVCLYFI SPTGHSLKTL
DLLTMKNLDS KVNIIPVIAK ADTVSKTELQ KFKIKLMSEL VSNGVQIYQF PTDDDTIAKV
NAAMNGQLPF AVVGSMDEVK VGNKMVKARQ YPWGVVQVEN ENHCDFVKLR EMLICTNMED
LREQTHTRHY ELYRRCKLEE MGFTDVGPEN KPVSLQETYE AKRHEFHGER QRKEEEMKQM
FVQRVKEKEA ILKEAERELQ AKFEHLKRLH QEERMKLEEK RRLLEEEIIA FSKKKATSEI
FHSQSFLATG SNLRKDKDRK KEPGCRFELL CIDVRACETN GGRKDAEKAP IFCKTEVPEH
RRSSSQANFI KKKLEVCFDF AVLLIFMEKY FQVQGQYISQ SE
//
