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Database: UniProt
Entry: A0A2I3TRM0_PANTR
LinkDB: A0A2I3TRM0_PANTR
Original site: A0A2I3TRM0_PANTR 
ID   A0A2I3TRM0_PANTR        Unreviewed;       777 AA.
AC   A0A2I3TRM0;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   05-JUN-2019, entry version 9.
DE   SubName: Full=ADAM metallopeptidase domain 7 {ECO:0000313|Ensembl:ENSPTRP00000091615};
GN   Name=ADAM7 {ECO:0000313|Ensembl:ENSPTRP00000091615,
GN   ECO:0000313|VGNC:VGNC:927};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
OC   Catarrhini; Hominidae; Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000091615, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000091615, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the
RT   human genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|Ensembl:ENSPTRP00000091615}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
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DR   EMBL; AACZ04065668; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSPTRT00000083239; ENSPTRP00000091615; ENSPTRG00000020086.
DR   VGNC; VGNC:927; ADAM7.
DR   GeneTree; ENSGT00940000161406; -.
DR   Proteomes; UP000002277; Chromosome 8.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:Ensembl.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   CDD; cd04269; ZnMc_adamalysin_II_like; 1.
DR   Gene3D; 3.40.390.10; -; 1.
DR   Gene3D; 4.10.70.10; -; 1.
DR   InterPro; IPR006586; ADAM_Cys-rich.
DR   InterPro; IPR018358; Disintegrin_CS.
DR   InterPro; IPR001762; Disintegrin_dom.
DR   InterPro; IPR036436; Disintegrin_dom_sf.
DR   InterPro; IPR024079; MetalloPept_cat_dom_sf.
DR   InterPro; IPR001590; Peptidase_M12B.
DR   InterPro; IPR002870; Peptidase_M12B_N.
DR   InterPro; IPR034027; Reprolysin_adamalysin.
DR   Pfam; PF08516; ADAM_CR; 1.
DR   Pfam; PF00200; Disintegrin; 1.
DR   Pfam; PF01562; Pep_M12B_propep; 1.
DR   Pfam; PF01421; Reprolysin; 1.
DR   PRINTS; PR00289; DISINTEGRIN.
DR   SMART; SM00608; ACR; 1.
DR   SMART; SM00050; DISIN; 1.
DR   SUPFAM; SSF57552; SSF57552; 1.
DR   PROSITE; PS50215; ADAM_MEPRO; 1.
DR   PROSITE; PS00427; DISINTEGRIN_1; 1.
DR   PROSITE; PS50214; DISINTEGRIN_2; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002277};
KW   Disulfide bond {ECO:0000256|PROSITE-ProRule:PRU00068,
KW   ECO:0000256|SAAS:SAAS00877335};
KW   Membrane {ECO:0000256|SAAS:SAAS01078504, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW   Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|SAAS:SAAS01078486,
KW   ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS01078482,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL        1     18       {ECO:0000256|SAM:SignalP}.
FT   CHAIN        19    777       {ECO:0000256|SAM:SignalP}.
FT                                /FTId=PRO_5014152023.
FT   TRANSMEM    669    690       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN      199    394       Peptidase M12B. {ECO:0000259|PROSITE:
FT                                PS50215}.
FT   DOMAIN      402    488       Disintegrin. {ECO:0000259|PROSITE:
FT                                PS50214}.
FT   REGION      757    777       Disordered. {ECO:0000256|MobiDB-lite:
FT                                A0A2I3TRM0}.
FT   DISULFID    460    480       {ECO:0000256|PROSITE-ProRule:PRU00068}.
SQ   SEQUENCE   777 AA;  88445 MW;  FEE3110BFFA94F06 CRC64;
     MLPGCIFLMI LLIPQVKEKF ILGVEGQQLV RPKKLPLIQK RDTGHTHDDD IPKTYEEELL
     YEIKLNRKTL VLHLLRSREF LGSNYSETFY SMKGEAFTRH PQIVDHCFYQ GSIVHEYDSA
     ASISTCNGLR GFFRINDQRY LIEPVKYSDE GEHLVFKYNL RMPYVANYSC TELNFTRKTV
     PGDNESEEDS KIKGIHDEKY VELFIVADDT VYRRNSHPHN KLRNRIWGMV NFVNMIYKTL
     NIHVTLVGIE IWTHEDKIEL YSNIETTLLH FSFWQEKILK TRKDFDHVVL LSGKWLYSHV
     QGISYPGGMC LPYYSTSIIK DLLPDTNIIA NRMAHQLGHN LGMQHDEFPC TCPSGKCVMD
     SDGSIPALKF SKCSQNQYHQ YLKDYKPTCM LNIPFPYNFH DFQFCGNKKL DEGEECDCGP
     AQECTNPCCD AHTCVLKPGF TCAEGECCES CQIKKAGSIC RPAKDECDFP EMCTGHSPAC
     PKDQFRVNGF PCKNSEGYCF MGKCPTREDQ CSELFDDEAI ESHDICYKMN TKGNKFGYCK
     NKENRFLPCE EKDVRCGKIY CTGGELSSLL GEDKTYHLKD PQQNATVKCK TIFLYHDSTD
     IGLVASGTKC GEGMVCNNGE CLNMEKVYIS TNCPSQCREN PVDGHGLQCH CEEGQEPVAC
     EETLNVTNIT VLVVVLVLVI VGIGVLILLV RYRKCIKLKQ VQSPPTETLG VENKGYFGDE
     QQIRTEPILP EIHFRNQRTP ESLESLATSF SSPHYITLKP ASKDSRGIAD PNQSAKW
//
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