ID A0A2I3TRU8_PANTR Unreviewed; 737 AA.
AC A0A2I3TRU8; A0A2J8KV73;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Ssemaphorin 4F {ECO:0000313|Ensembl:ENSPTRP00000091948.1};
GN Name=SEMA4F {ECO:0000313|Ensembl:ENSPTRP00000091948.1,
GN ECO:0000313|VGNC:VGNC:6657};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000091948.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000091948.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000091948.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
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DR EMBL; AACZ04063590; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_016804336.1; XM_016948847.1.
DR AlphaFoldDB; A0A2I3TRU8; -.
DR Ensembl; ENSPTRT00000089510.1; ENSPTRP00000091948.1; ENSPTRG00000012103.6.
DR GeneID; 470411; -.
DR CTD; 10505; -.
DR VGNC; VGNC:6657; SEMA4F.
DR GeneTree; ENSGT00940000159592; -.
DR OrthoDB; 5342713at2759; -.
DR Proteomes; UP000002277; Chromosome 2A.
DR Bgee; ENSPTRG00000012103; Expressed in superior frontal gyrus and 17 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR GO; GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd11261; Sema_4F; 1.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR016201; PSI.
DR InterPro; IPR047085; Sem4F_Sema_dom.
DR InterPro; IPR045791; Sema4F_C.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR PANTHER; PTHR11036:SF72; SEMAPHORIN-4F; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 1.
DR Pfam; PF19428; Sema4F_C; 1.
DR SMART; SM00423; PSI; 1.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Developmental protein {ECO:0000256|ARBA:ARBA00022473};
KW Differentiation {ECO:0000256|ARBA:ARBA00022782};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..737
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5015082088"
FT TRANSMEM 626..647
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..477
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
FT REGION 663..692
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 737 AA; 79926 MW; 804F4FC0137CBE04 CRC64;
MPASAARPLP GPGQLTASPF PLLLLAVLSG PVSGRVPRSV PRTSLPISEA DSCLTRFAVP
HTYNYSVLLV DPASHTLYVG ARDTIFALSL PFSGERPRRI DWMVPEAHRQ NCRKKGKKED
VSRFQQVERL ESGRGKCPFE PAQRSAAVMA GGVLYAATVK NYLGTEPIIT RAVGRAEDWI
RTDTLPSWLN APAFVAAVAL SPAEWGDEDG DDEIYFFFTE TSRAFDSYER IKVPRVARVC
AGDLGGRKTL QQRWTTFLKA DLLCPGPEHG RASSVLQDVA VLRPELGAGT PIFYGIFSSQ
WEGATISAVC AFRPQDIRTV LNGPFRELKH DCNRGLPVVD NDVPQPRPGE CITNNMKLRH
FGSSLSLPDR VLTFIRDHPL MDRPVFPADG HPLLVTTDTA YLRVVAHRVT SLSGKEYDVL
YLGTEDGHLH RAVRIGAQLS VLEDLALFPE PQPVENMKLY HSWLLVGSRT EVTQVNTTNC
GRLQSCSECI LAQDPVCAWS FRLDECVAHA GEHRGLVQDI ESADVSSLCP KEPGERPVVF
EVPVATAAHV VLPCSPSSAW ASCVWHQPSG VTALTPRRDG LEVVVTPGAM GAYACECQEG
GAARVVAAYS LVWGSQRDAV SRAHTVGAGL AGFLLGVLAA SLTLILIGRR QQRRRQRELL
ARDKVGLDLG APPSGTTSYS QDPPSPSPED ERLPLALAKR GSGFGGFSPP FLLDPCPSPA
HIRLTGAPLA TCDETSI
//
