ID A0A2I3TT98_PANTR Unreviewed; 537 AA.
AC A0A2I3TT98;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 18.
DE SubName: Full=Cell division cycle 45 {ECO:0000313|Ensembl:ENSPTRP00000092211.1};
GN Name=CDC45 {ECO:0000313|Ensembl:ENSPTRP00000092211.1,
GN ECO:0000313|VGNC:VGNC:5243};
OS Pan troglodytes (Chimpanzee).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Pan.
OX NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000092211.1, ECO:0000313|Proteomes:UP000002277};
RN [1] {ECO:0000313|Ensembl:ENSPTRP00000092211.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15164055; DOI=10.1038/nature02564;
RA Watanabe H., Fujiyama A., Hattori M., Taylor T.D., Toyoda A., Kuroki Y.,
RA Noguchi H., BenKahla A., Lehrach H., Sudbrak R., Kube M., Taenzer S.,
RA Galgoczy P., Platzer M., Scharfe M., Nordsiek G., Bloecker H., Hellmann I.,
RA Khaitovich P., Paabo S., Reinhardt R., Zheng H.-J., Zhang X.-L., Zhu G.-F.,
RA Wang B.-F., Fu G., Ren S.-X., Zhao G.-P., Chen Z., Lee Y.-S., Cheong J.-E.,
RA Choi S.-H., Wu K.-M., Liu T.-T., Hsiao K.-J., Tsai S.-F., Kim C.-G.,
RA Oota S., Kitano T., Kohara Y., Saitou N., Park H.-S., Wang S.-Y.,
RA Yaspo M.-L., Sakaki Y.;
RT "DNA sequence and comparative analysis of chimpanzee chromosome 22.";
RL Nature 429:382-388(2004).
RN [2] {ECO:0000313|Ensembl:ENSPTRP00000092211.1, ECO:0000313|Proteomes:UP000002277}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=16136131; DOI=10.1038/nature04072;
RG Chimpanzee sequencing and analysis consortium;
RT "Initial sequence of the chimpanzee genome and comparison with the human
RT genome.";
RL Nature 437:69-87(2005).
RN [3] {ECO:0000313|Ensembl:ENSPTRP00000092211.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC45 family.
CC {ECO:0000256|ARBA:ARBA00010727}.
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DR EMBL; AACZ04061726; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04061727; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AACZ04061728; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A2I3TT98; -.
DR PaxDb; 9598-ENSPTRP00000024215; -.
DR Ensembl; ENSPTRT00000092415.1; ENSPTRP00000092211.1; ENSPTRG00000014064.6.
DR VGNC; VGNC:5243; CDC45.
DR GeneTree; ENSGT00390000009662; -.
DR Proteomes; UP000002277; Chromosome 22.
DR Bgee; ENSPTRG00000014064; Expressed in testis and 14 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR InterPro; IPR003874; CDC45.
DR PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR Pfam; PF02724; CDC45; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000002277}.
SQ SEQUENCE 537 AA; 62014 MW; 96624276AA871470 CRC64;
MFVSDFRKEF YEVVQSQRVL LFVASDVDAL CACKILQALF QCDHVQYTLV PVSGWQELET
AFLEHKEQFH YFILINCGAN VDLLDILQPD EDTIFFVCDT HRPVNVINVY NDTQVLFVLC
PQTLCTFYCH RPKLTSSNRE IVEQTMRRRQ RREWEARRRD ILFDYEQYEY HGTSSAMVMF
ELAWMLSKDL NDMLWWAIVG LTDQWVQDKI TQMKYVTDVG VLQRHVSRHN HRNEDEENTL
SVDCTRISFE YDLRLVLYQH WSLHDSLCNT SYTAARFKLW SVHGQKRLQE FLADMGLPLK
QVKQKFQAMD ISLKENLREM IEESANKFGM KDMRVQTFSI HFGFKHKFLA SDVVFATMSL
MESPEKDGSG TDHFIQALDS LSRSNLDKLY HGLELAKKQL RATQQTIASC LCTNLVISQG
PFLYCSLMEG TPDVMLFSRP ASLSLLSKHL LKSFVCSTKN RRCKLLPLVM AAPLSVEHGT
VTVVGIPPET DMSVLGRGKA AESTSSRMLH NHFDLSVIEL KAEDRSKFLD ALISLLS
//
