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Database: UniProt
Entry: A0A2I3TV88_PANTR
LinkDB: A0A2I3TV88_PANTR
Original site: A0A2I3TV88_PANTR 
ID   A0A2I3TV88_PANTR        Unreviewed;       319 AA.
AC   A0A2I3TV88; A0A2J8NYU3;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   11-DEC-2019, entry version 9.
DE   SubName: Full=SAM pointed domain containing ETS transcription factor {ECO:0000313|Ensembl:ENSPTRP00000093195};
DE   SubName: Full=SPDEF isoform 1 {ECO:0000313|EMBL:PNI76943.1};
GN   Name=SPDEF {ECO:0000313|Ensembl:ENSPTRP00000093195,
GN   ECO:0000313|VGNC:VGNC:3710};
GN   ORFNames=CK820_G0007032 {ECO:0000313|EMBL:PNI76943.1};
OS   Pan troglodytes (Chimpanzee).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pan.
OX   NCBI_TaxID=9598 {ECO:0000313|Ensembl:ENSPTRP00000093195, ECO:0000313|Proteomes:UP000002277};
RN   [1] {ECO:0000313|Ensembl:ENSPTRP00000093195, ECO:0000313|Proteomes:UP000002277}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16136131; DOI=10.1038/nature04072;
RG   Chimpanzee sequencing and analysis consortium;
RT   "Initial sequence of the chimpanzee genome and comparison with the human
RT   genome.";
RL   Nature 437:69-87(2005).
RN   [2] {ECO:0000313|EMBL:PNI76943.1}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Yerkes chimp pedigree #C0471 {ECO:0000313|EMBL:PNI76943.1};
RC   TISSUE=Blood {ECO:0000313|EMBL:PNI76943.1};
RA   Pollen A., Hastie A., Hormozdiari F., Dougherty M., Liu R., Chaisson M.,
RA   Hoppe E., Hill C., Pang A., Hillier L., Baker C., Armstrong J.,
RA   Shendure J., Paten B., Wilson R., Chao H., Schneider V., Ventura M.,
RA   Kronenberg Z., Murali S., Gordon D., Cantsilieris S., Munson K., Nelson B.,
RA   Raja A., Underwood J., Diekhans M., Fiddes I., Haussler D., Eichler E.;
RT   "High-resolution comparative analysis of great ape genomes.";
RL   Submitted (DEC-2017) to the EMBL/GenBank/DDBJ databases.
RN   [3] {ECO:0000313|Ensembl:ENSPTRP00000093195}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (JAN-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   EMBL; AACZ04022819; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; NBAG03000221; PNI76943.1; -; Genomic_DNA.
DR   Ensembl; ENSPTRT00000110097; ENSPTRP00000093195; ENSPTRG00000018065.
DR   VGNC; VGNC:3710; SPDEF.
DR   GeneTree; ENSGT00940000157549; -.
DR   Proteomes; UP000002277; Chromosome 6.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000002277}.
FT   DOMAIN          129..213
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          233..316
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          77..101
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..19
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   319 AA;  35686 MW;  E713355B88C21ACD CRC64;
     MGSASPGLSS VSPSHLLLPP DTVSRTGLEK AAAGAVGLER RDWSPSPPAT PEQGLSAFYL
     SYFDMLYPED SSWAVKAPGA SSREEPPEEP EQCPVIDSQA PGGSLDLVPG GLTLEEHSLE
     QVQSMVVGEV LKDIETACKL LNITADPMDW SSSNVQKWLL WTEHQYRLPP VGKAFQELAG
     KELCAMSEEQ FRQRSPLGGD VLHAHLDIWK SASTSEESWT DSEVDSSCSG QPIHLWQFLK
     ELLLKPHSYG RFIRWLNKEK GIFKIEDSAQ VARLWGIRKN RPAMNYDKLS RSIRQYYKKG
     IIRKPDISQR LVYQFVHPI
//
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