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Database: UniProt
Entry: A0A2I4C8J7_9TELE
LinkDB: A0A2I4C8J7_9TELE
Original site: A0A2I4C8J7_9TELE 
ID   A0A2I4C8J7_9TELE        Unreviewed;       457 AA.
AC   A0A2I4C8J7;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   11-DEC-2019, entry version 9.
DE   SubName: Full=Friend leukemia integration 1 transcription factor isoform X2 {ECO:0000313|RefSeq:XP_013876295.1};
GN   Name=fli1 {ECO:0000313|RefSeq:XP_013876295.1};
OS   Austrofundulus limnaeus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae;
OC   Austrofundulus.
OX   NCBI_TaxID=52670 {ECO:0000313|Proteomes:UP000192220, ECO:0000313|RefSeq:XP_013876295.1};
RN   [1] {ECO:0000313|RefSeq:XP_013876295.1}
RP   IDENTIFICATION.
RC   STRAIN=Quisiro {ECO:0000313|RefSeq:XP_013876295.1};
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_013876295.1};
RG   RefSeq;
RL   Submitted (JAN-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594387}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|RuleBase:RU004019,
CC       ECO:0000256|SAAS:SAAS00594391}.
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DR   RefSeq; XP_013876295.1; XM_014020841.1.
DR   GeneID; 106526278; -.
DR   CTD; 2313; -.
DR   OrthoDB; 1113327at2759; -.
DR   Proteomes; UP000192220; Genome assembly.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   CDD; cd08541; SAM_PNT-FLI-1; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   Gene3D; 1.10.150.50; -; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR035575; Fli-1.
DR   InterPro; IPR003118; Pointed_dom.
DR   InterPro; IPR013761; SAM/pointed_sf.
DR   InterPro; IPR035573; SAM_PNT-FLI-1.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849:SF161; PTHR11849:SF161; 1.
DR   Pfam; PF00178; Ets; 1.
DR   Pfam; PF02198; SAM_PNT; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SMART; SM00251; SAM_PNT; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF47769; SSF47769; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
DR   PROSITE; PS51433; PNT; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594397};
KW   Nucleus {ECO:0000256|RuleBase:RU004019, ECO:0000256|SAAS:SAAS00594400};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192220}.
FT   DOMAIN          118..204
FT                   /note="PNT"
FT                   /evidence="ECO:0000259|PROSITE:PS51433"
FT   DOMAIN          286..366
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          36..60
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          205..267
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..60
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..267
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   457 AA;  51580 MW;  913B18BDE268A88E CRC64;
     MFQTVPDTSS YVKEALSVVS EDQSLFEPPY AAAAPLPKTD MTASGTQDYG QTHKINPLPP
     QQEWINQPVR VNVKREYEHM NGSRESPVDC SVGKCNKLVA GNDASQMTYG SYMDEKNAPP
     PNMTTNERRV IVPADPSLWS QDHVRQWLEW AIKEYGLLEI DTSMFQNTDG KDLCKMNKDD
     FLRLTSMYNA DVLLSHLNYL RESSSSLSYN TPSHTDPSPR LAAKEDPSYD AVRRTGWSSN
     MHSGKGSPVL NQNVTKSTEQ PRAQPDPYQI LGPTSSRLAN PGSGQIQLWQ FLLELLSDSA
     NAGCITWEGT NGEFKMTDPD EVARRWGERK SKPNMNYDKL SRALRYYYDK NIMTKVHGKR
     YAYKFDFHGI AQALQPHPTE SSMYKYPSDL TYVPSYHAHQ QKVNFVSPHP SSMPVTSSNF
     FGPTAQYWSS PTASIYPNPN VPRHPNTHVP SHLGGYY
//
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