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Database: UniProt
Entry: A0A2I4CQH5_9TELE
LinkDB: A0A2I4CQH5_9TELE
Original site: A0A2I4CQH5_9TELE 
ID   A0A2I4CQH5_9TELE        Unreviewed;       435 AA.
AC   A0A2I4CQH5;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   13-NOV-2019, entry version 12.
DE   SubName: Full=ATP-sensitive inward rectifier potassium channel 11-like {ECO:0000313|RefSeq:XP_013882244.1, ECO:0000313|RefSeq:XP_013882245.1};
GN   Name=LOC106531031 {ECO:0000313|RefSeq:XP_013882244.1,
GN   ECO:0000313|RefSeq:XP_013882245.1};
OS   Austrofundulus limnaeus.
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Cyprinodontiformes; Rivulidae;
OC   Austrofundulus.
OX   NCBI_TaxID=52670 {ECO:0000313|Proteomes:UP000192220, ECO:0000313|RefSeq:XP_013882245.1};
RN   [1] {ECO:0000313|RefSeq:XP_013882244.1, ECO:0000313|RefSeq:XP_013882245.1}
RP   IDENTIFICATION.
RC   STRAIN=Quisiro {ECO:0000313|RefSeq:XP_013882244.1,
RC   ECO:0000313|RefSeq:XP_013882245.1};
RC   TISSUE=Liver {ECO:0000313|RefSeq:XP_013882244.1,
RC   ECO:0000313|RefSeq:XP_013882245.1};
RG   RefSeq;
RL   Submitted (JAN-2018) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU003822};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU003822}.
CC   -!- SIMILARITY: Belongs to the inward rectifier-type potassium channel
CC       (TC 1.A.2.1) family. {ECO:0000256|RuleBase:RU003822,
CC       ECO:0000256|SAAS:SAAS00549381}.
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DR   RefSeq; XP_013882244.1; XM_014026790.1.
DR   RefSeq; XP_013882245.1; XM_014026791.1.
DR   GeneID; 106531031; -.
DR   KEGG; alim:106531031; -.
DR   KO; K05004; -.
DR   OrthoDB; 956263at2759; -.
DR   Proteomes; UP000192220; Genome assembly.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005242; F:inward rectifier potassium channel activity; IEA:InterPro.
DR   GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.40.1400; -; 1.
DR   InterPro; IPR014756; Ig_E-set.
DR   InterPro; IPR041647; IRK_C.
DR   InterPro; IPR016449; K_chnl_inward-rec_Kir.
DR   InterPro; IPR013518; K_chnl_inward-rec_Kir_cyto.
DR   InterPro; IPR040445; Kir_TM.
DR   PANTHER; PTHR11767; PTHR11767; 1.
DR   Pfam; PF01007; IRK; 1.
DR   Pfam; PF17655; IRK_C; 1.
DR   PIRSF; PIRSF005465; GIRK_kir; 1.
DR   PRINTS; PR01320; KIRCHANNEL.
DR   SUPFAM; SSF81296; SSF81296; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000192220};
KW   Ion channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434609, ECO:0000313|RefSeq:XP_013882244.1,
KW   ECO:0000313|RefSeq:XP_013882245.1};
KW   Ion transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434639};
KW   Membrane {ECO:0000256|SAAS:SAAS00434581, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434575};
KW   Potassium transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434641};
KW   Reference proteome {ECO:0000313|Proteomes:UP000192220};
KW   Transmembrane {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00434543, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAAS:SAAS00036756,
KW   ECO:0000256|SAM:Phobius};
KW   Transport {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00036755};
KW   Voltage-gated channel {ECO:0000256|RuleBase:RU003822,
KW   ECO:0000256|SAAS:SAAS00048561}.
FT   TRANSMEM     73     94       Helical. {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM    149    173       Helical. {ECO:0000256|SAM:Phobius}.
FT   DOMAIN       37    178       IRK. {ECO:0000259|Pfam:PF01007}.
FT   DOMAIN      186    356       IRK_C. {ECO:0000259|Pfam:PF17655}.
FT   REGION      392    435       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    404    435       Polyampholyte. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   SITE        165    165       Role in the control of polyamine-mediated
FT                                channel gating and in the blocking by
FT                                intracellular magnesium.
FT                                {ECO:0000256|PIRSR:PIRSR005465-1}.
SQ   SEQUENCE   435 AA;  48583 MW;  2283E52A4A63C078 CRC64;
     MLARKGLLPD GFLLTRLAED QNQPNRSHSR SQRARFITKT GSCNVAHKNI REQGRFLQDV
     FTTMVDLKWQ HSFLIFTSAF LCSWMLFAMA WWLLAFAHGD LEPRDLDSEP GPVPCVTAIH
     SFTSAFLFSI EVQVTIGFGG RMVTEECPVA IIVLIIQNIL GLIINAVMLG CVFMKTAQAN
     RRAETLIFSR NAVIATRNGR PTFMFRVGDL RKSMIISATV QLQVIRRTVT SEGEVIPVCQ
     LDIQVENPLR SNGIFLVSPL IISHTIERGS PLYELSAQSL ASEDLEIIVI LEGVVETTGI
     SMQARTSYTP EEILWGRRFV SIITEEDGHY CVDYSKFGNT VSVRMSSLSA KELDQTRGVQ
     EGTSDSQLQG WGLVRAGRGG FRRGGRACVG SAPQPWYAQS ESPNKEAEQK DQKKTVQLEV
     IGRQMEEDEL RDMSD
//
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