ID A0A2I4DKS3_JUGRE Unreviewed; 448 AA.
AC A0A2I4DKS3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=Purple acid phosphatase {ECO:0000256|RuleBase:RU361203};
DE EC=3.1.3.2 {ECO:0000256|RuleBase:RU361203};
GN Name=LOC108981111 {ECO:0000313|RefSeq:XP_018807738.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018807738.1};
RN [1] {ECO:0000313|RefSeq:XP_018807738.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018807738.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a phosphate monoester + H2O = an alcohol + phosphate;
CC Xref=Rhea:RHEA:15017, ChEBI:CHEBI:15377, ChEBI:CHEBI:30879,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:67140; EC=3.1.3.2;
CC Evidence={ECO:0000256|ARBA:ARBA00000032,
CC ECO:0000256|RuleBase:RU361203};
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|ARBA:ARBA00001962};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallophosphoesterase superfamily. Purple
CC acid phosphatase family. {ECO:0000256|ARBA:ARBA00008723,
CC ECO:0000256|RuleBase:RU361203}.
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DR RefSeq; XP_018807738.1; XM_018952193.2.
DR AlphaFoldDB; A0A2I4DKS3; -.
DR STRING; 51240.A0A2I4DKS3; -.
DR EnsemblPlants; Jr03_01610_p1; cds.Jr03_01610_p1; Jr03_01610.
DR GeneID; 108981111; -.
DR Gramene; Jr03_01610_p1; cds.Jr03_01610_p1; Jr03_01610.
DR KEGG; jre:108981111; -.
DR InParanoid; A0A2I4DKS3; -.
DR OrthoDB; 5485592at2759; -.
DR Proteomes; UP000235220; Chromosome 3.
DR GO; GO:0003993; F:acid phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd00839; MPP_PAPs; 1.
DR Gene3D; 3.60.21.10; -; 1.
DR Gene3D; 2.60.40.380; Purple acid phosphatase-like, N-terminal; 1.
DR InterPro; IPR004843; Calcineurin-like_PHP_ApaH.
DR InterPro; IPR029052; Metallo-depent_PP-like.
DR InterPro; IPR041792; MPP_PAP.
DR InterPro; IPR039331; PPA-like.
DR InterPro; IPR008963; Purple_acid_Pase-like_N.
DR InterPro; IPR015914; Purple_acid_Pase_N.
DR InterPro; IPR025733; Purple_acid_PPase_C_dom.
DR PANTHER; PTHR22953; ACID PHOSPHATASE RELATED; 1.
DR PANTHER; PTHR22953:SF7; PURPLE ACID PHOSPHATASE 22; 1.
DR Pfam; PF00149; Metallophos; 1.
DR Pfam; PF14008; Metallophos_C; 1.
DR Pfam; PF16656; Pur_ac_phosph_N; 1.
DR SUPFAM; SSF56300; Metallo-dependent phosphatases; 1.
DR SUPFAM; SSF49363; Purple acid phosphatase, N-terminal domain; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361203};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU361203};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT CHAIN 28..448
FT /note="Purple acid phosphatase"
FT /evidence="ECO:0000256|RuleBase:RU361203"
FT /id="PRO_5013985368"
FT DOMAIN 54..141
FT /note="Purple acid phosphatase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16656"
FT DOMAIN 150..340
FT /note="Calcineurin-like phosphoesterase"
FT /evidence="ECO:0000259|Pfam:PF00149"
FT DOMAIN 355..418
FT /note="Iron/zinc purple acid phosphatase-like C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14008"
SQ SEQUENCE 448 AA; 51108 MW; D8BDA551FACAE62D CRC64;
MENLYPRANF SLILTLFLIF FPQLLHSQTK NGAFSRQPPR PMVFTPHNRP DSDPQQVHIS
LAGIDHIRVS WITEAKHAKS VVEYGKESGK YNALETGEHK SYTYFFYHSG EIHHVKIGPL
EPSTTYFYRC GGSGPEFSFR TPPSGFPIEF AVVGDLGQTE WTASTLQHID SKDYDVFLLP
GDLSYADGQQ PLWDSFGRLV EPYATRRPWM VTEGNHEIET IPIIHPYGFR SYNARWRMPH
EESGSTSNLY YSFDVAGTHI IMLGSYTEFD ADSSQYKWLE ADLANVDRKK TPWIFVLLHA
PWYNTNTAHQ GEGESMRKAM EELLYKARVD VVFAGHVHAY ERFTRIFHNK ENQCGPMYVT
VGDGGNREGL ALTFKNPTSP LSLFREASFG HGRLSVLNQT HAHWSWHRNN DSNAVVADQV
WLESLSISKA CWETLEDQGL SSSLKDEL
//
