ID A0A2I4DRH3_JUGRE Unreviewed; 827 AA.
AC A0A2I4DRH3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cullin-4-like {ECO:0000313|RefSeq:XP_018809750.1};
GN Name=LOC108982749 {ECO:0000313|RefSeq:XP_018809750.1};
GN ORFNames=F2P56_006968 {ECO:0000313|EMBL:KAF5475127.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018809750.1};
RN [1] {ECO:0000313|EMBL:KAF5475127.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5475127.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5475127.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5475127.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018809750.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018809750.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the cullin family.
CC {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC ECO:0000256|RuleBase:RU003829}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LIHL02000003; KAF5475127.1; -; Genomic_DNA.
DR RefSeq; XP_018809750.1; XM_018954205.2.
DR STRING; 51240.A0A2I4DRH3; -.
DR EnsemblPlants; Jr03_14420_p1; cds.Jr03_14420_p1; Jr03_14420.
DR GeneID; 108982749; -.
DR Gramene; Jr03_14420_p1; cds.Jr03_14420_p1; Jr03_14420.
DR KEGG; jre:108982749; -.
DR OrthoDB; 21270at2759; -.
DR Proteomes; UP000235220; Chromosome 3.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031625; F:ubiquitin protein ligase binding; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR045093; Cullin.
DR InterPro; IPR016157; Cullin_CS.
DR InterPro; IPR016158; Cullin_homology.
DR InterPro; IPR036317; Cullin_homology_sf.
DR InterPro; IPR001373; Cullin_N.
DR InterPro; IPR019559; Cullin_neddylation_domain.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11932; CULLIN; 1.
DR PANTHER; PTHR11932:SF123; CULLIN-4; 1.
DR Pfam; PF00888; Cullin; 1.
DR Pfam; PF10557; Cullin_Nedd8; 1.
DR SMART; SM00182; CULLIN; 1.
DR SMART; SM00884; Cullin_Nedd8; 1.
DR SUPFAM; SSF75632; Cullin homology domain; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS01256; CULLIN_1; 1.
DR PROSITE; PS50069; CULLIN_2; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT DOMAIN 471..700
FT /note="Cullin family profile"
FT /evidence="ECO:0000259|PROSITE:PS50069"
FT REGION 1..47
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 75..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..24
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 94490 MW; 03EC5C5CEE47F403 CRC64;
MSLPNKRSAT TTSDATTIHT PTSSPPSSHF PPMKKAKSQA VALDPRNGLH HHQDLSAATT
ANNSNNVVVF DPSSMALDDD LKPDDSSAPP RSVAANLARK KAQPPQPAKK LVIKLVKAKP
TLPANFEELT WAKLKSAISA IFLKQPDPID SEILYQAVND LCLHKLGGNL YRRIEKECEL
HISSALQSLV GQSPDLVVFL SLVERCWQDL CDQMLLIRGI ALYLDRTYVK QTPNVRSLWD
MGLQLFRKHL SSSPEVEHKT VTGLLRMIEK ERLGEAVDRT LLNHLLKMFT ALGIYLESFE
KPFLECTSEF YAAEGMKYMQ QSDVPDYLKH VEARLHEEHE RCLLYLDAST RKPLIATAEK
QLLERHISAI LDKGFMMLMN GNRIEDLRRM YSLFSRVNAL ESLRQALSSY IRRTGQGVVM
DEEKDKDMVA SLLEFKALLD TIWEESFSKN ESFCNTIKEA FEHLINLRQN RPAELIAKFL
DEKLRAGNKG TSEEELEGTL DKVLVLFRFI QGKDVFEAFY KKDLAKRLLL GKSASIDAEK
SMISKLKTEC GSQFTNKLEG MFKDIELSKE INESFKQSSQ ARTKLPSGIE MSVHVLTTGY
WPTYPPMDVR LPHELNVYQD IFKEFYLSKY SGRRLMWQNS LGYCVLKAEF PKGKKELAVS
LFQTVVLMLF NDAENLSFQD IKDSTGIEDK ELRRTLQSLA CGKVRVLLKL PKGRDVEDDD
TFVFNEGFTA PLYRIKVNAI QMKETVEENT STTERVFQDR QYQVDAAIVR IMKTRKVLSH
TLLITELFQQ LKFPIKPADL KKRIESLIDR EYLERDKNNP QIYNYLA
//
