ID A0A2I4E1S3_JUGRE Unreviewed; 760 AA.
AC A0A2I4E1S3;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cation/H(+) antiporter 3-like {ECO:0000313|RefSeq:XP_018813337.1};
GN Name=LOC108985486 {ECO:0000313|RefSeq:XP_018813337.1};
GN ORFNames=F2P56_010998 {ECO:0000313|EMBL:KAF5470485.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018813337.1};
RN [1] {ECO:0000313|EMBL:KAF5470485.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5470485.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5470485.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5470485.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018813337.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018813337.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the monovalent cation:proton antiporter 2 (CPA2)
CC transporter (TC 2.A.37) family. CHX (TC 2.A.37.4) subfamily.
CC {ECO:0000256|ARBA:ARBA00038341}.
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DR EMBL; LIHL02000005; KAF5470485.1; -; Genomic_DNA.
DR RefSeq; XP_018813337.1; XM_018957792.2.
DR EnsemblPlants; Jr05_07830_p1; cds.Jr05_07830_p1; Jr05_07830.
DR GeneID; 108985486; -.
DR Gramene; Jr05_07830_p1; cds.Jr05_07830_p1; Jr05_07830.
DR KEGG; jre:108985486; -.
DR OrthoDB; 1083521at2759; -.
DR Proteomes; UP000235220; Chromosome 5.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0012505; C:endomembrane system; IBA:GO_Central.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:1902600; P:proton transmembrane transport; IEA:InterPro.
DR GO; GO:0006885; P:regulation of pH; IBA:GO_Central.
DR Gene3D; 1.20.1530.20; -; 1.
DR InterPro; IPR006153; Cation/H_exchanger.
DR InterPro; IPR038770; Na+/solute_symporter_sf.
DR PANTHER; PTHR32468; CATION/H + ANTIPORTER; 1.
DR PANTHER; PTHR32468:SF17; CATION_H(+) ANTIPORTER 4; 1.
DR Pfam; PF00999; Na_H_Exchanger; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 67..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 166..185
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 206..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..255
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 262..283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 318..339
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 14..406
FT /note="Cation/H+ exchanger"
FT /evidence="ECO:0000259|Pfam:PF00999"
SQ SEQUENCE 760 AA; 84469 MW; F022F4DAB842979B CRC64;
MSSFSLPVLE MQLVLIFTIT QASYRIFRPM GVPPFASQLI TGMILSPSFL GRFTIFKDLF
TIRSQEIIGM LAGFGHVLFL ILSAVKMDIG NIERLGKKAL YTGIASLLAP TLIGSYLLHA
KLAKSWLNGE ELLNMSFLLA IHSLTSFPVV IYLLEHLKML NSELGQFGLS AALVSDFSSL
TLLILGSIAK LGKVKGSMYA IKEAGAIFLF LLFVVFAFRP AMFWIVRQTP EGKPVKNIYI
YIIMVVMLFS GLFTLSHSMS IFLGPYLVGL AIPYGLPLGP IMIKKLNSFT HNVFHPLFVT
TCAMRTDLRL LNFNGRPMIY NAILVSATFL AKMLASFVLS LYYSKMPFND ALAIALIMSF
KGAVHLGFYT FFGFFPTGTL RDQSLSFECV VLLLNVIILP ILVKFLYDPS RKYACYQKRN
ILGCRRNQEL RVLVCIRRST NLSAVIRLLG AASSSPARPR LAIYVLHLIK LAEEASRPVF
ISHQMQKKIP FRNSYSEIVI KAFRHFKRDI QGTAVSVKLF TVVRPSKVMA EGICSLALDK
LASFIILPFH RKWSVDGCVA SEDSTIQTLN RNVLEHAPCS VGILVDRGHD YNLGLSSTLM
LSSDSSTYSV AMIFLGGNDD REALSFAKRM SNKYSKISLT VIHLVSPGSN ELDVTNDLEN
VLDSLALKDV ILNNVGDEYV RYLEEIVQDG PQTTSTVCSM VDEYDLIIVG RRHEMESPQT
SGLAELSTFP ELGIIGDLLA SSDLNTRTSV LVVQQQKMII
//
