ID A0A2I4EV30_JUGRE Unreviewed; 544 AA.
AC A0A2I4EV30;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=LOC108992959 {ECO:0000313|RefSeq:XP_018823250.1};
GN Synonyms=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=F2P56_020823 {ECO:0000313|EMBL:KAF5460994.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018823250.1};
RN [1] {ECO:0000313|EMBL:KAF5460994.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5460994.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5460994.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5460994.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018823250.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018823250.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
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DR EMBL; LIHL02000009; KAF5460994.1; -; Genomic_DNA.
DR RefSeq; XP_018823250.1; XM_018967705.2.
DR EnsemblPlants; Jr09_14280_p1; cds.Jr09_14280_p1; Jr09_14280.
DR GeneID; 108992959; -.
DR Gramene; Jr09_14280_p1; cds.Jr09_14280_p1; Jr09_14280.
DR OrthoDB; 1062103at2759; -.
DR Proteomes; UP000235220; Chromosome 9.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR31942:SF77; MLO-LIKE PROTEIN 14; 1.
DR Pfam; PF03094; Mlo; 1.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..76
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 147..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..311
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 395..415
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 515..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 62021 MW; 43D49EEAE19EEABA CRC64;
MRSLALTPTW SVATVLTIFV AISFLVERSI HRLSSWLQKT NRKPLLAAVE KMKEELMLLG
FISLLLTASS SMISNICIPS KFYDSKFAPC TISVLKGKSS QHRNLLMVSV LPHSFRRMLS
DLNEKNTCSK DHEPFVSYQG LEQLHRFIFV MAITHISYSC LTMLLAIVKI HSWRVWEIEA
HMDRQGSLTE ITREQTLQRQ SAFVKFHASN PLVRNSFLVW VTCFFRQFGH SMVRADYLTL
REGFIMNHNL KQKYDFHGYM VRSMEEEFQM IVGVSGPLWG FVVAFMLFDV NGSNLYFWIA
IIPIALVLLV GTKLQHVIAT LALENAGITG FFTGAKLRPR DDLFWFKKPE LLLSLIHFIL
FQNAFELASF FWFWWQFGYN SCFIGNHLLV YTRLALGFAG QFLCSYSTLP LYALVTQMGT
NYKAALIPQG IRETVHVWRN KARRRRLGIF TDNSTVHTDT STVMSIEEDR ELLDDAPETT
TGEFTEIEMQ PTPASATNLS TVANETSSRV VAPLLQSSAS VSSSVTLSSR TEGIPRSYSL
PTRR
//
