ID A0A2I4EVC1_JUGRE Unreviewed; 317 AA.
AC A0A2I4EVC1;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Methyl-CpG-binding domain-containing protein 2-like isoform X3 {ECO:0000313|RefSeq:XP_018823353.1};
GN Name=LOC108993041 {ECO:0000313|RefSeq:XP_018823353.1};
GN ORFNames=F2P56_034666 {ECO:0000313|EMBL:KAF5445624.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018823353.1};
RN [1] {ECO:0000313|EMBL:KAF5445624.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5445624.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5445624.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5445624.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018823353.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018823353.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; LIHL02000015; KAF5445624.1; -; Genomic_DNA.
DR RefSeq; XP_018823353.1; XM_018967808.2.
DR EnsemblPlants; Jr15_11840_p1; cds.Jr15_11840_p1; Jr15_11840.
DR GeneID; 108993041; -.
DR Gramene; Jr15_11840_p1; cds.Jr15_11840_p1; Jr15_11840.
DR OrthoDB; 1217115at2759; -.
DR Proteomes; UP000235220; Chromosome 15.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd01396; MeCP2_MBD; 1.
DR Gene3D; 3.30.40.100; -; 1.
DR InterPro; IPR016177; DNA-bd_dom_sf.
DR InterPro; IPR001739; Methyl_CpG_DNA-bd.
DR InterPro; IPR011124; Znf_CW.
DR PANTHER; PTHR12396:SF0; METHYL-CPG BINDING DOMAIN PROTEIN-LIKE, ISOFORM C; 1.
DR PANTHER; PTHR12396; METHYL-CPG BINDING PROTEIN, MBD; 1.
DR Pfam; PF01429; MBD; 1.
DR Pfam; PF07496; zf-CW; 1.
DR SMART; SM00391; MBD; 1.
DR SUPFAM; SSF54171; DNA-binding domain; 1.
DR PROSITE; PS50982; MBD; 1.
DR PROSITE; PS51050; ZF_CW; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 106..165
FT /note="CW-type"
FT /evidence="ECO:0000259|PROSITE:PS51050"
FT DOMAIN 171..245
FT /note="MBD"
FT /evidence="ECO:0000259|PROSITE:PS50982"
FT REGION 34..102
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..317
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 317 AA; 35956 MW; 4AD5FF8E595ECF3C CRC64;
MRRDKLGWSN LLQQEEKDIT GSSFLANYES NLQELEDVSS SSSSSEDESL ETEDEDEQSN
ENASKQLVLY DPLTNGTDEI EPVPDPIQSQ TPFRRYSAPN SSPRVLPSVG AFTVQCASCF
KWRLIPTKEK YEAIREHILE QPFYCNTARE WRADISCDDP TDISQDDSRL WAIDKPNIAQ
PPPGWQRLLR IRGEGSTKFA DIYYQAPSGK KLRSMVEIQK YLLEHPEYMS DDVSLSQFSF
QIPKPLQENY VRKRPPQLKA SHVTRPLEPG EASPLALMGP DNCPDSQLTR PGLPPNFEDP
VFDPVGRPAK KRSRPPG
//
