ID   A0A2I4F3B3_JUGRE        Unreviewed;       540 AA.
AC   A0A2I4F3B3;
DT   28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT   28-FEB-2018, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   RecName: Full=type I protein arginine methyltransferase {ECO:0000256|ARBA:ARBA00011925};
DE            EC=2.1.1.319 {ECO:0000256|ARBA:ARBA00011925};
GN   Name=LOC108995079 {ECO:0000313|RefSeq:XP_018826128.1};
OS   Juglans regia (English walnut).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fagales; Juglandaceae; Juglans.
OX   NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018826128.1};
RN   [1] {ECO:0000313|RefSeq:XP_018826128.1}
RP   IDENTIFICATION.
RC   TISSUE=Leaves {ECO:0000313|RefSeq:XP_018826128.1};
RG   RefSeq;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) +
CC         N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-
CC         homocysteine; Xref=Rhea:RHEA:48096, Rhea:RHEA-COMP:10532, Rhea:RHEA-
CC         COMP:11991, ChEBI:CHEBI:15378, ChEBI:CHEBI:29965, ChEBI:CHEBI:57856,
CC         ChEBI:CHEBI:59789, ChEBI:CHEBI:61897; EC=2.1.1.319;
CC         Evidence={ECO:0000256|ARBA:ARBA00001817};
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC       Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR   RefSeq; XP_018826128.1; XM_018970583.2.
DR   AlphaFoldDB; A0A2I4F3B3; -.
DR   STRING; 51240.A0A2I4F3B3; -.
DR   EnsemblPlants; Jr07_18690_p1; cds.Jr07_18690_p1; Jr07_18690.
DR   GeneID; 108995079; -.
DR   Gramene; Jr07_18690_p1; cds.Jr07_18690_p1; Jr07_18690.
DR   KEGG; jre:108995079; -.
DR   InParanoid; A0A2I4F3B3; -.
DR   OrthoDB; 197898at2759; -.
DR   Proteomes; UP000235220; Chromosome 7.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR   GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR025799; Arg_MeTrfase.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   PANTHER; PTHR11006:SF10; HISTONE-ARGININE METHYLTRANSFERASE CARMER-RELATED; 1.
DR   PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR   Pfam; PF06325; PrmA; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51678; SAM_MT_PRMT; 1.
PE   4: Predicted;
KW   Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW   Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW   ECO:0000313|RefSeq:XP_018826128.1};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PROSITE-ProRule:PRU01015};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW   Transferase {ECO:0000256|PROSITE-ProRule:PRU01015}.
FT   REGION          521..540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        523..540
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   540 AA;  60470 MW;  9E04326FF4D53801 CRC64;
     MEGPTGQKLK QQEFALVSVS ELSPSSSTSP SKLVVARFCA DSGISELRFH KEPESIATRN
     VDLRTARLFK LGPVQSVCIS EGSEASKETS YSRGITVQFR NEEESRTFHS AFEQWKKEVS
     QGKQLSNGTV LDTRSKFDDK IEPSSAKMYF HYYGQLLHQQ NMLQDYVRTG TYYAAVVENR
     TDFIGRVVVD VGAGSGILSL FAAQAGAKHV YAVEASEMAE YAQKLIAGNP SLGQRITVVK
     GKVEEVELPE KADILISEPM GTLLVNERML ESYVIARDRF LVPNGKMFPT VGRIHMAPFS
     DEYLFVEIAN KALFWQQHNY YGVDLTPLHG SAFQGYFSQP VVDAFDPRLL VAPPIFHGID
     FMKIKEEELY EIDIPLRFTS SVGARVHGLA CWFDVLFNGS TVQRWLSTAP GAPTTHWYQL
     RCVLSQPIYV MAGQEITGRL HMIAHNAQSY TIYLTLSAKM WGPGAEQGGI LQTSSCKLDL
     KEPYYRMSQP QAYPIVQDQQ SHQLISTQDI PIQSHDLEEP ELMQQPSPNS GTHLNIMENV
//