ID A0A2I4F774_JUGRE Unreviewed; 1138 AA.
AC A0A2I4F774;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=DNA repair protein REV1 {ECO:0000256|ARBA:ARBA00020399, ECO:0000256|PIRNR:PIRNR036573};
DE EC=2.7.7.- {ECO:0000256|PIRNR:PIRNR036573};
GN Name=LOC108996187 {ECO:0000313|RefSeq:XP_018827499.1};
GN ORFNames=F2P56_028772 {ECO:0000313|EMBL:KAF5448216.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018827499.1};
RN [1] {ECO:0000313|EMBL:KAF5448216.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5448216.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5448216.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5448216.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018827499.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018827499.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: Deoxycytidyl transferase involved in DNA repair. Transfers a
CC dCMP residue from dCTP to the 3'-end of a DNA primer in a template-
CC dependent reaction. May assist in the first step in the bypass of
CC abasic lesions by the insertion of a nucleotide opposite the lesion.
CC Required for normal induction of mutations by physical and chemical
CC agents. {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PIRNR:PIRNR036573}.
CC -!- SIMILARITY: Belongs to the DNA polymerase type-Y family.
CC {ECO:0000256|ARBA:ARBA00010945, ECO:0000256|PIRNR:PIRNR036573}.
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DR EMBL; LIHL02000013; KAF5448216.1; -; Genomic_DNA.
DR RefSeq; XP_018827499.1; XM_018971954.2.
DR RefSeq; XP_018827501.1; XM_018971956.1.
DR STRING; 51240.A0A2I4F774; -.
DR EnsemblPlants; Jr13_01440_p1; cds.Jr13_01440_p1; Jr13_01440.
DR GeneID; 108996187; -.
DR Gramene; Jr13_01440_p1; cds.Jr13_01440_p1; Jr13_01440.
DR KEGG; jre:108996187; -.
DR OrthoDB; 169741at2759; -.
DR Proteomes; UP000235220; Chromosome 13.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003684; F:damaged DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0016779; F:nucleotidyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0042276; P:error-prone translesion synthesis; IEA:InterPro.
DR CDD; cd17719; BRCT_Rev1; 1.
DR CDD; cd01701; PolY_Rev1; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.40.1170.60; -; 1.
DR Gene3D; 6.10.250.1490; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 3.30.1490.100; DNA polymerase, Y-family, little finger domain; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036775; DNA_pol_Y-fam_lit_finger_sf.
DR InterPro; IPR017961; DNA_pol_Y-fam_little_finger.
DR InterPro; IPR012112; REV1.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR001126; UmuC.
DR PANTHER; PTHR45990; DNA REPAIR PROTEIN REV1; 1.
DR PANTHER; PTHR45990:SF1; DNA REPAIR PROTEIN REV1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF00817; IMS; 1.
DR Pfam; PF11799; IMS_C; 1.
DR Pfam; PF21704; POLH-Rev1_HhH; 1.
DR PIRSF; PIRSF036573; REV1; 1.
DR SMART; SM00292; BRCT; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF100879; Lesion bypass DNA polymerase (Y-family), little finger domain; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS50173; UMUC; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|PIRNR:PIRNR036573};
KW DNA repair {ECO:0000256|PIRNR:PIRNR036573};
KW DNA synthesis {ECO:0000256|ARBA:ARBA00022634,
KW ECO:0000256|PIRNR:PIRNR036573};
KW DNA-binding {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleotidyltransferase {ECO:0000256|PIRNR:PIRNR036573};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR036573};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transferase {ECO:0000256|PIRNR:PIRNR036573}.
FT DOMAIN 102..193
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 390..570
FT /note="UmuC"
FT /evidence="ECO:0000259|PROSITE:PS50173"
FT REGION 1..64
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1138 AA; 126451 MW; 1EC0C3E58A965792 CRC64;
MSLDSSRSAN SSGGHRSKRS FNNSTSSNPS NYSNGNNKKK AKPSQETLGA ASWGANSVPP
SRSSFRKAPF SDFGSYMMEK NRKLHDQFDA EASTSSHSCS GSGKPIFHGI SIFVDGFTIP
SSQDLRGYML KHGGRFENYF SRRRVTHIIC SNLPDSKLKN LRSFSGGLPV VKPLWILDSV
VANKLLSWVP YQLDQLANNQ PRLSAFFAPK SSSVSKDVKP EGSFFKGGTS TDAYFSDLGE
SSEHSRQISR ETDNLVNRNS NASLVMEPTS SCGRPFELTM EKPNNIDEDN KRSVRNELQS
SPYQSSALAT SNFVENHDMT GSPGSTVSGL SNHRHSTIED PNFVENYFKN SRLHFIGTWR
NRYRKRFSSL SNGFKCRSSN IEASAQKTAI VHVDMDCFFV SVVIRDRPEL KDKPVAVCHS
DNPKGTAEIS SANYPARDYG IRAGMFVRDA KARCPHLVIF PYNFEAYEEV ADQFYNILHK
HCNKVQAVSC DEAFLDFTDS VEDPQILASR IRKEVIETTR CTASAGIAGN MLMARLATRT
AKPDGQFFIP PERVDDHLSQ LPIKALPGIG HVLEEKLKKH NVWTCGQLRM ISKESLQKDF
GMKTGEMLWD YSRGVDDRLV GVIQVSKSIG AEVNWGVRFK DVKDSQNFLS NLCKEVSLRL
HGCGVQGRTF TLKIKKRRKD AEEPIKYMGC GDCENLSHST TVPVATDDVE VLQRISKQLF
GYFHLDVKEI RGIGLQVSRL ESAGSLKQGL ERNSLKSWLS SAAASTEEAC NNSCTALVRS
DTDCEGQGNE ILGKICASSV WPSIEMDNNT SNGEAFLNQV SEPPPLCHLD KEVLESLPSE
IFSELNDIYS GKLVDLITKS NGKSENISSS LSNSHVQVEG AMKKGHMVLC SDPFLQHEIP
VEDKHIAMED QAVLVSGAES NNVVLPDSGI QKIDLMPLSL SQVDATVLQQ LPEEVKADIL
QLLPAHRKQD FSSNALSGPS KETPLESLGT KTAEYHSVSK GCVSENNLWA GTPLQWVVKF
KVSNCLILNV LAEMYYELGS TGTLSAILQR VISLPKHQLD ANRDSWDEAT YNLCDLLKQY
IKRKIEFDIE EIYICFCLLR RFAMKSEVFL QVYTNVFPYL QASVGENYGG NLHMSLKT
//
