ID A0A2I4FRW7_JUGRE Unreviewed; 371 AA.
AC A0A2I4FRW7;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=uroporphyrinogen-III C-methyltransferase {ECO:0000256|ARBA:ARBA00012162};
DE EC=2.1.1.107 {ECO:0000256|ARBA:ARBA00012162};
GN Name=LOC109001507 {ECO:0000313|RefSeq:XP_018834373.1};
GN ORFNames=F2P56_031518 {ECO:0000313|EMBL:KAF5445834.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018834373.1};
RN [1] {ECO:0000313|EMBL:KAF5445834.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5445834.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5445834.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5445834.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018834373.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018834373.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the precorrin methyltransferase family.
CC {ECO:0000256|RuleBase:RU003960}.
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DR EMBL; LIHL02000014; KAF5445834.1; -; Genomic_DNA.
DR RefSeq; XP_018834373.1; XM_018978828.2.
DR STRING; 51240.A0A2I4FRW7; -.
DR EnsemblPlants; Jr14_00280_p1; cds.Jr14_00280_p1; Jr14_00280.
DR GeneID; 109001507; -.
DR Gramene; Jr14_00280_p1; cds.Jr14_00280_p1; Jr14_00280.
DR KEGG; jre:109001507; -.
DR OrthoDB; 296644at2759; -.
DR Proteomes; UP000235220; Chromosome 14.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0004851; F:uroporphyrin-III C-methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IBA:GO_Central.
DR CDD; cd11642; SUMT; 1.
DR InterPro; IPR000878; 4pyrrol_Mease.
DR InterPro; IPR035996; 4pyrrol_Methylase_sf.
DR InterPro; IPR014777; 4pyrrole_Mease_sub1.
DR InterPro; IPR014776; 4pyrrole_Mease_sub2.
DR InterPro; IPR006366; CobA/CysG_C.
DR InterPro; IPR003043; Uropor_MeTrfase_CS.
DR NCBIfam; TIGR01469; cobA_cysG_Cterm; 1.
DR PANTHER; PTHR45790:SF3; S-ADENOSYL-L-METHIONINE-DEPENDENT UROPORPHYRINOGEN III METHYLTRANSFERASE, CHLOROPLASTIC; 1.
DR PANTHER; PTHR45790; SIROHEME SYNTHASE-RELATED; 1.
DR Pfam; PF00590; TP_methylase; 1.
DR SUPFAM; SSF53790; Tetrapyrrole methylase; 1.
DR PROSITE; PS00839; SUMT_1; 1.
DR PROSITE; PS00840; SUMT_2; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000256|RuleBase:RU003960};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003960}.
FT DOMAIN 119..331
FT /note="Tetrapyrrole methylase"
FT /evidence="ECO:0000259|Pfam:PF00590"
SQ SEQUENCE 371 AA; 40622 MW; C1341154C13CE62E CRC64;
MALADRLQFL SPSLSSIHFR KPNSINIHPL CSLHYDSFFT SYSSPFTEKH SIQRYQRDQW
LYKNQLEQIT SCSFPPDSHL NRENNIALQL PELKKLLQVL REKRESEGCS KGKYGPGNVF
LVGTGPGDPE LLTLKAVRVI QSADLLLYDR LVSNDVLDLI GPDARLLYVG KTAGYHSRTQ
EEIHELLLSF AEAGATVVRL KGGDPLVFGR GGEEMEFLQQ QGIQVKVIPG ITAASGIAAE
LGIPLTQRGV ANSVKFLTGH ARKGGTDPLF VAENAADPDS TLVVYMGLST FPSLSLKLLH
HGLPPYTPAV AVERGTTPQQ RMVFAELKDL AQQITSAQLI SPTLIIIGKV VALSPLWSIS
LKETSSLVEA K
//
