ID A0A2I4GRK6_JUGRE Unreviewed; 885 AA.
AC A0A2I4GRK6;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 02-DEC-2020, sequence version 2.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Extra-large guanine nucleotide-binding protein 1-like {ECO:0000313|RefSeq:XP_018846534.2};
GN Name=LOC109010226 {ECO:0000313|RefSeq:XP_018846534.2};
GN ORFNames=F2P56_029249 {ECO:0000313|EMBL:KAF5448744.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018846534.2};
RN [1] {ECO:0000313|EMBL:KAF5448744.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5448744.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5448744.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5448744.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018846534.2}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018846534.2};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the G-alpha family.
CC {ECO:0000256|ARBA:ARBA00005804}.
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DR EMBL; LIHL02000013; KAF5448744.1; -; Genomic_DNA.
DR RefSeq; XP_018846534.2; XM_018990989.2.
DR STRING; 51240.A0A2I4GRK6; -.
DR EnsemblPlants; Jr13_06670_p1; cds.Jr13_06670_p1; Jr13_06670.
DR Gramene; Jr13_06670_p1; cds.Jr13_06670_p1; Jr13_06670.
DR KEGG; jre:109010226; -.
DR OrthoDB; 1221906at2759; -.
DR Proteomes; UP000235220; Chromosome 13.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0005834; C:heterotrimeric G-protein complex; IBA:GO_Central.
DR GO; GO:0001664; F:G protein-coupled receptor binding; IBA:GO_Central.
DR GO; GO:0031683; F:G-protein beta/gamma-subunit complex binding; IBA:GO_Central.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0003924; F:GTPase activity; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0007188; P:adenylate cyclase-modulating G protein-coupled receptor signaling pathway; IBA:GO_Central.
DR Gene3D; 1.10.400.10; GI Alpha 1, domain 2-like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR001019; Gprotein_alpha_su.
DR InterPro; IPR011025; GproteinA_insert.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR PANTHER; PTHR36486; OS01G0977800 PROTEIN; 1.
DR PANTHER; PTHR36486:SF4; PH DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00503; G-alpha; 1.
DR SMART; SM00275; G_alpha; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF47895; Transducin (alpha subunit), insertion domain; 1.
DR PROSITE; PS51882; G_ALPHA; 1.
PE 3: Inferred from homology;
KW GTP-binding {ECO:0000256|ARBA:ARBA00023134};
KW Lipoprotein {ECO:0000256|ARBA:ARBA00022707};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Myristate {ECO:0000256|ARBA:ARBA00022707};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transducer {ECO:0000256|ARBA:ARBA00023224};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT REGION 131..188
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 152..172
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 173..188
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 885 AA; 99246 MW; 2259028825E66E0B CRC64;
MAALLRKLRP AVSAIPENDD DEYSRSDYSI ALVYNGPPVS YDIPQVIPVD ISQIPVAAPV
SSASLINNLA LPVIQPIVKS RPLNQKSPTL DSSGVLACGN GYEPKPTLSD EIESSGALRY
SGIVDGSLEL STGSGEFEVD NDKEGEGAHD YMNPTNSEST ESGLSSPGRS SEIFSCREDD
GDNEAPHHVK RPSIVTFRDP ESRDVIADVE LYHSEDESID VSPKVAINVK KGVCYRCLKG
NRFTEKEVCI VCGAKYCYDC LIRAMGSMPE GRKCVTCIGY SIDEARRGKL GKGSRLLKRL
LTDREVKRIM EAEIFCEANQ VQAQVVFVNG EPLTQEELVQ LQSCKNPPRK LRPGCYWYDK
VSGLWGREGE KPSQIISAQL NVGGQIKLNA SNGNTNVLIN NREITKEELW MLKAAGVPCE
GSPHFWVSDD GSYQEEGQNN IKGKIWDKTR TKLVCTVLSL PVPPNSQNSS GEEVGGFIPA
SVIQKSIHKL FLVGYNKSGS GTIYKQAKLL YDVPFSEDER QAIKFVIQRN LYMYLSFILE
GRERFEKQSL LEKKKGRVIN KSGPSDNTSL TVDNTIYAIG PRVKAFSDRL LQVMALGTLE
PATFSEYAPR VQELWEEAAI KATYNRRNEL EMLPREATYF LDRAVEIVRT DYEPSEMDIL
YAEGITLCNS LACLEFSFPK SIRDDSVDPA YQHDPSLRYK LIRVHPRSLG ANCKWLDMFE
DADILLFCVA LTDYDEFYED FNGVSTNKMM ASKQLFESIV THPTFENKNF LLILTKFDLL
EEKIDQVPLT RCEWFHDFHP VTTKNRHNTT NPSLAHRAFH YIAIKFKTLF RSLADGKLFV
SSVTGLENDT VDEALRYARE IVLWEEEKPC FINDLSSTDI EASSS
//
