ID A0A2I4GS46_JUGRE Unreviewed; 1048 AA.
AC A0A2I4GS46;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Histone-lysine N-methyltransferase ATX3 isoform X2 {ECO:0000313|RefSeq:XP_018846721.1};
GN Name=LOC109010367 {ECO:0000313|RefSeq:XP_018846721.1};
GN ORFNames=F2P56_026823 {ECO:0000313|EMBL:KAF5451745.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018846721.1};
RN [1] {ECO:0000313|EMBL:KAF5451745.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5451745.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5451745.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5451745.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018846721.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018846721.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; LIHL02000012; KAF5451745.1; -; Genomic_DNA.
DR RefSeq; XP_018846721.1; XM_018991176.2.
DR EnsemblPlants; Jr12_05260_p1; cds.Jr12_05260_p1; Jr12_05260.
DR GeneID; 109010367; -.
DR Gramene; Jr12_05260_p1; cds.Jr12_05260_p1; Jr12_05260.
DR OrthoDB; 304343at2759; -.
DR Proteomes; UP000235220; Chromosome 12.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0048188; C:Set1C/COMPASS complex; IEA:UniProt.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006325; P:chromatin organization; IEA:UniProtKB-KW.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR GO; GO:0051171; P:regulation of nitrogen compound metabolic process; IEA:UniProt.
DR CDD; cd15663; ePHD_ATX3_4_5_like; 1.
DR CDD; cd15495; PHD_ATX3_4_5_like; 1.
DR CDD; cd15517; PHD_TCF19_like; 1.
DR CDD; cd20143; PWWP_AtATX3-like; 1.
DR CDD; cd10518; SET_SETD1-like; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 3.10.390.10; SAND domain-like; 1.
DR Gene3D; 2.170.270.10; SET domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR041955; ATX3/4/5_ePHD.
DR InterPro; IPR042011; ATX3/4/5_PHD.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR025780; Hist-Lys_N-MeTrfase_ATX.
DR InterPro; IPR003616; Post-SET_dom.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR010919; SAND-like_dom_sf.
DR InterPro; IPR001214; SET_dom.
DR InterPro; IPR046341; SET_dom_sf.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF92; HISTONE-LYSINE N-METHYLTRANSFERASE ATX3; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF00855; PWWP; 1.
DR Pfam; PF00856; SET; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SMART; SM00508; PostSET; 1.
DR SMART; SM00293; PWWP; 1.
DR SMART; SM00317; SET; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR SUPFAM; SSF82199; SET domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS50868; POST_SET; 1.
DR PROSITE; PS50812; PWWP; 1.
DR PROSITE; PS51566; SAM_MT43_TRX_MLL; 1.
DR PROSITE; PS50280; SET; 1.
DR PROSITE; PS50016; ZF_PHD_2; 2.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 246..315
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT DOMAIN 429..485
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 613..664
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 667..782
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 906..1023
FT /note="SET"
FT /evidence="ECO:0000259|PROSITE:PS50280"
FT DOMAIN 1032..1048
FT /note="Post-SET"
FT /evidence="ECO:0000259|PROSITE:PS50868"
FT REGION 20..50
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1048 AA; 118948 MW; 0019C39BD500AA14 CRC64;
MIIKRTMKPE MPNLKRCKLE DSDWEEEDDD RACSVNPKRR KPNGYLSVGS GEVKDFSNGS
GYLWRSESEG SYWGGEFELN SKQLNGKGEI QQCSERFRPP LLKSSRGRVQ MLPSKFYDSV
VDVWKTGESK FNSKDSSLEG DEMEVKDMEF IKRSEEDKSR FKNLKLCPNS EKEREGKAGY
VGYKNFYRRK YLNSSSSTAK SFGLNSPALT RSNGYKPKYS FTGIERLAKG NAGKRKEVYK
PEDFALGDIV WAKCGRRYPT WPAVVIDPIS QAPETVLSCC VPGAICVMFF GYSKNGTQRD
YAWVKQGMLF PFLEFMDRYK GQTQLYKSKL SDFQRALEEA LLAENGILDT NLGAGEIANP
ETNPKEMQEA TDSNLDQQCS GNQDEHCKDP IPCDGCGLFL PSRTMKKMKG PTCETLLLCK
HCAKLRKSRQ YCGICKKIWH HSDGGDWVCC DGCNVWVHAD CDNISSELFK DLEHIDYYCP
DCKEKSNSEL SATGKGQPKV NSVENSGQTV LPEVVTVVCN GMEGTYIRSL HLVMCKCGLC
GSKKQTPSEW ERHTGCRAKK WKYSVKVKDT MLPLEKWISE YNAHGMDPLK FDKQQLLTFL
QETYEPVHAK WTTERCAVCR WVEDWDDNKI IICNRCQIAI HQECYGTKSV QDFTSWVCRV
CESPNIKREC CLCPVEGGAL KPTDVDSLWA HVTCAWFRPE VGFLNHEKME PAVGILRIPS
NSFLKRCIIC KQSHGSCTQC CKCATYFHVM CAYRAGYCME LHSWEKNGTQ MTKKLIYCAV
HRVPNPDSVV AVHTPSGVFS ARSLLQNQKG CFRGSRLVSL KKTELLESSN LESDEFEPLS
AAKCRVFKRL KNKRAEGQPL FHRPMGPSHH SLDAINSLST NNELEGPKIF TSLKERLYHL
QRTENHRVGF GKSGIHGWGL FARRNIQGGE MVVEYRGEQV RRSVADLREA KYGLEGKDCY
LFKISEEVVI DATDKGNIAR LINHSCMPNC YARIMSLGDE ESRIVLIAKT NVSAGEELTY
DYLFDPDERD ELKVPCLCGA PNCRKFMN
//
