ID A0A2I4GV92_JUGRE Unreviewed; 520 AA.
AC A0A2I4GV92;
DT 28-FEB-2018, integrated into UniProtKB/TrEMBL.
DT 28-FEB-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=MLO-like protein {ECO:0000256|RuleBase:RU280816};
GN Name=LOC109011174 {ECO:0000313|RefSeq:XP_018847812.1};
GN Synonyms=MLO {ECO:0000256|RuleBase:RU280816};
GN ORFNames=F2P56_007650 {ECO:0000313|EMBL:KAF5475893.1};
OS Juglans regia (English walnut).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fagales; Juglandaceae; Juglans.
OX NCBI_TaxID=51240 {ECO:0000313|Proteomes:UP000235220, ECO:0000313|RefSeq:XP_018847812.1};
RN [1] {ECO:0000313|EMBL:KAF5475893.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5475893.1};
RA Martinez-Garcia P.J., Crepeau M.W., Puiu D., Gonzalez-Ibeas D., Whalen J.,
RA Stevens K., Paul R., Butterfield T., Britton M., Reagan R., Chakraborty S.,
RA Walawage S.L., Vasquez-Gross H.A., Cardeno C., Famula R., Pratt K.,
RA Kuruganti S., Aradhya M.K., Leslie C.A., Dandekar A.M., Salzberg S.L.,
RA Wegrzyn J.L., Langley C.H., Neale D.B.;
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KAF5475893.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Leaves {ECO:0000313|EMBL:KAF5475893.1};
RA Marrano A., Britton M., Zimin A.V., Zaini P.A., Workman R., Puiu D.,
RA Bianco L., Allen B.J., Troggio M., Leslie C.A., Timp W., Dendekar A.,
RA Salzberg S.L., Neale D.B.;
RT "Walnut 2.0.";
RL Submitted (MAR-2020) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_018847812.1}
RP IDENTIFICATION.
RC TISSUE=Leaves {ECO:0000313|RefSeq:XP_018847812.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: May be involved in modulation of pathogen defense and leaf
CC cell death. {ECO:0000256|RuleBase:RU280816}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU280816}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU280816}.
CC -!- DOMAIN: The C-terminus contains a calmodulin-binding domain, which
CC binds calmodulin in a calcium-dependent fashion.
CC {ECO:0000256|RuleBase:RU280816}.
CC -!- SIMILARITY: Belongs to the MLO family. {ECO:0000256|ARBA:ARBA00006574,
CC ECO:0000256|RuleBase:RU280816}.
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DR EMBL; LIHL02000003; KAF5475893.1; -; Genomic_DNA.
DR RefSeq; XP_018847812.1; XM_018992267.2.
DR STRING; 51240.A0A2I4GV92; -.
DR EnsemblPlants; Jr03_21980_p1; cds.Jr03_21980_p1; Jr03_21980.
DR GeneID; 109011174; -.
DR Gramene; Jr03_21980_p1; cds.Jr03_21980_p1; Jr03_21980.
DR KEGG; jre:109011174; -.
DR OrthoDB; 368831at2759; -.
DR Proteomes; UP000235220; Chromosome 3.
DR Proteomes; UP000619265; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0009607; P:response to biotic stimulus; IEA:UniProtKB-KW.
DR InterPro; IPR004326; Mlo.
DR PANTHER; PTHR31942:SF59; MLO-LIKE PROTEIN; 1.
DR PANTHER; PTHR31942; MLO-LIKE PROTEIN 1; 1.
DR Pfam; PF03094; Mlo; 2.
PE 3: Inferred from homology;
KW Calmodulin-binding {ECO:0000256|RuleBase:RU280816};
KW Membrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Pathogenesis-related protein {ECO:0000256|ARBA:ARBA00023265,
KW ECO:0000256|RuleBase:RU280816};
KW Plant defense {ECO:0000256|RuleBase:RU280816};
KW Reference proteome {ECO:0000313|Proteomes:UP000235220};
KW Transmembrane {ECO:0000256|RuleBase:RU280816, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|RuleBase:RU280816,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 129..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 281..307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..400
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 497..520
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 520 AA; 59337 MW; 9D093ACC62CDBB32 CRC64;
MAGGDSSDRS LEYTPTWALA AVCFFFISIS IILEQSIHLL TKWLKRHRKN ALFDAVEKLK
SELMLLGFLS LLLAVTQDRI SKICIPVDAA NVMLPCRKST NNHGAAPSVD SCSSEGKVAL
VTQDGLHQLH IFIFALAVMQ IVYCVLTLAL GRAKMSRWEA WEKETQTTEY QVANDPNRFR
FTRQTTFGRR HMSSCTGTPF QLWIKCFFRQ FFHSVAKVDY LTLRHGFISA HLSASNNFDF
RKYIQRTLEE DFKQVVGISP LMWFLVVILM LVDVYGWHVF LWVSCIPLLV VLVLGAKLEV
IVARMALQIK DQNSVIKGTP LVRPNDSLFW FGHPGFVLTL IHYTLFVNAF ELAFFIWVTI
QFGFNSCYHE HTAIIVIRIV LAVTVQVLCS YITLPLYALV TQMGSNFRSK VLEEQIANII
RQWHAEVRER RKKQELFIPS PARKSLSTEW SPRRSSTSAH GVSSFQRPRY MRSDSINKGK
IVELGERSDQ IVVLKEEAAA GSSRRPSRAV VLELPTARRQ
//
