ID A0A2I5TI45_SERS3 Unreviewed; 449 AA.
AC A0A2I5TI45;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Channel protein TolC {ECO:0000313|EMBL:AUH04233.1};
GN ORFNames=CWC46_08925 {ECO:0000313|EMBL:AUG99913.1}, Ser39006_008930
GN {ECO:0000313|EMBL:AUH04233.1};
OS Serratia sp. (strain ATCC 39006).
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
OC Yersiniaceae; Serratia.
OX NCBI_TaxID=104623 {ECO:0000313|EMBL:AUH04233.1, ECO:0000313|Proteomes:UP000017700};
RN [1] {ECO:0000313|EMBL:AUH04233.1, ECO:0000313|Proteomes:UP000017700}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39006 {ECO:0000313|EMBL:AUH04233.1}, and ATCC 39006 / SC
RC 11482 {ECO:0000313|Proteomes:UP000017700};
RX PubMed=24336377; DOI=10.1128/genomeA.01039-13;
RA Fineran P.C., Iglesias Cans M.C., Ramsay J.P., Wilf N.M., Cossyleon D.,
RA McNeil M.B., Williamson N.R., Monson R.E., Becher S.A., Stanton J.A.,
RA Brugger K., Brown S.D., Salmond G.P.;
RT "Draft genome sequence of Serratia sp. strain ATCC 39006, a model bacterium
RT for analysis of the biosynthesis and regulation of prodigiosin, a
RT carbapenem, and gas vesicles.";
RL Genome Announc. 1:E01039-E01039(2013).
RN [2] {ECO:0000313|EMBL:AUH04233.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39006 {ECO:0000313|EMBL:AUH04233.1};
RA Wang G., Yang Y., Su Y.;
RL Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:AUG99913.1, ECO:0000313|Proteomes:UP000233778}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 39006 {ECO:0000313|EMBL:AUG99913.1,
RC ECO:0000313|Proteomes:UP000233778};
RA Hampton H.G., Jackson S.A., Jauregui R., Poulter G.T.M., Salmond G.P.C.,
RA Fineran P.C.;
RT "Complete genome sequence of Serratia sp. ATCC 39006 LacA.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:AUH04233.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=ATCC 39006 {ECO:0000313|EMBL:AUH04233.1};
RA Hampton H.G., Jackson S.A., Jauregui R., Poulter G.T.M., Salmond G.P.C.,
RA Fineran P.C.;
RT "Complete genome sequence of Serratia sp. ATCC 39006.";
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the outer membrane factor (OMF) (TC 1.B.17)
CC family. {ECO:0000256|ARBA:ARBA00007613}.
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DR EMBL; CP025085; AUG99913.1; -; Genomic_DNA.
DR EMBL; CP025084; AUH04233.1; -; Genomic_DNA.
DR RefSeq; WP_021016936.1; NZ_CP025085.1.
DR AlphaFoldDB; A0A2I5TI45; -.
DR STRING; 104623.Ser39006_03675; -.
DR KEGG; sera:Ser39006_008930; -.
DR KEGG; serq:CWC46_08925; -.
DR OrthoDB; 8683954at2; -.
DR Proteomes; UP000017700; Chromosome.
DR Proteomes; UP000233778; Chromosome.
DR GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-KW.
DR GO; GO:0015562; F:efflux transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1600.10; Outer membrane efflux proteins (OEP); 1.
DR InterPro; IPR003423; OMP_efflux.
DR InterPro; IPR010130; T1SS_OMP_TolC.
DR NCBIfam; TIGR01844; type_I_sec_TolC; 1.
DR PANTHER; PTHR30026:SF20; OUTER MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR30026; OUTER MEMBRANE PROTEIN TOLC; 1.
DR Pfam; PF02321; OEP; 2.
DR SUPFAM; SSF56954; Outer membrane efflux proteins (OEP); 1.
PE 3: Inferred from homology;
KW Cell outer membrane {ECO:0000256|ARBA:ARBA00023237};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000017700};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT SIGNAL 1..21
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 22..449
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036041091"
FT REGION 63..88
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..84
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 449 AA; 50228 MW; BD624F29D8A338DB CRC64;
MPHKYSFVLL PLLMASSMSF ADTLREAIED TLHTHPEVSA AINSRLSAEQ DMRSAEGGYL
PNISANAGIG KENTDSASTR ALGTDSDKLN RRESSISLSQ MVFDGFATSS EVGRQKATVN
SRAYKVLNTS ENRALDAIQA YLDVLQRQEY VRLAEANLLS HERIYDQIKL RTEQGVGRLA
DLEQAQARLA QARNNALTEK TNLTDSQTTY YSTIGKEPEN LQIPTQSASQ LPDSLDKARK
IMLTNSPILK SAEADIIATE KQYQASKAGF YPRVNVELSR SMGDNIDGAR GTDNEWQAML
RMRYNLYEGG STKATMESKA YQVKEAQDVR NNTLRLLNEE LRLAWSAVNN ARQQLPIAEE
YAERSQQVRN AYQKQFSLGE RTLLDVLDSE NELFTAQRRM VEIRFTEMFS EYRLKARMGN
LLASLSIPAP AASQSLSEVK TQVELPSLN
//
