ID   A0A2I6UHX1_9CAUD        Unreviewed;       168 AA.
AC   A0A2I6UHX1;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=dihydrofolate reductase {ECO:0000256|ARBA:ARBA00012856};
DE            EC=1.5.1.3 {ECO:0000256|ARBA:ARBA00012856};
GN   ORFNames=BSP10_176 {ECO:0000313|EMBL:AUO79579.1};
OS   Bacillus phage BSP10.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Herelleviridae; Bastillevirinae; Nitunavirus.
OX   NCBI_TaxID=2069312 {ECO:0000313|EMBL:AUO79579.1, ECO:0000313|Proteomes:UP000241565};
RN   [1] {ECO:0000313|EMBL:AUO79579.1, ECO:0000313|Proteomes:UP000241565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Ghosh K., Kim K.-P.;
RT   "Complete genome sequence of Bacillus phage BSP10.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; MF422185; AUO79579.1; -; Genomic_DNA.
DR   Proteomes; UP000241565; Genome.
DR   GO; GO:0004146; F:dihydrofolate reductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0006545; P:glycine biosynthetic process; IEA:InterPro.
DR   GO; GO:0006730; P:one-carbon metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0046654; P:tetrahydrofolate biosynthetic process; IEA:InterPro.
DR   CDD; cd00209; DHFR; 1.
DR   Gene3D; 3.40.430.10; Dihydrofolate Reductase, subunit A; 1.
DR   InterPro; IPR012259; DHFR.
DR   InterPro; IPR024072; DHFR-like_dom_sf.
DR   InterPro; IPR001796; DHFR_dom.
DR   PANTHER; PTHR48069; DIHYDROFOLATE REDUCTASE; 1.
DR   PANTHER; PTHR48069:SF3; DIHYDROFOLATE REDUCTASE; 1.
DR   Pfam; PF00186; DHFR_1; 1.
DR   PIRSF; PIRSF000194; DHFR; 1.
DR   PRINTS; PR00070; DHFR.
DR   SUPFAM; SSF53597; Dihydrofolate reductase-like; 1.
DR   PROSITE; PS51330; DHFR_2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000241565}.
FT   DOMAIN          2..160
FT                   /note="DHFR"
FT                   /evidence="ECO:0000259|PROSITE:PS51330"
SQ   SEQUENCE   168 AA;  19956 MW;  B759CAA16F34EA23 CRC64;
     MHVALIAATG LNREIGAGNR LLWDIKEDMN WFRQKTKNKV VVMGRKTYES IGKPLKGRVN
     VVLTHNKEYD PHPDVLVRHN LEDIFFEFRN ELEIMVIGGE TIYNQFFPYA NRIYLTQVEK
     TYEEADAFFP EFDRSIWNRY FYQDGSEDIG IKYNFSVYKK RLKLEGED
//