ID A0A2I7N605_9NEIS Unreviewed; 417 AA.
AC A0A2I7N605;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Citrate-proton symporter {ECO:0000313|EMBL:AUR51903.1};
GN ORFNames=CUN60_06190 {ECO:0000313|EMBL:AUR51903.1};
OS Aquella oligotrophica.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Aquella.
OX NCBI_TaxID=2067065 {ECO:0000313|EMBL:AUR51903.1, ECO:0000313|Proteomes:UP000236655};
RN [1] {ECO:0000313|Proteomes:UP000236655}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 100970 {ECO:0000313|Proteomes:UP000236655};
RA Chan K.G., Lee L.S.;
RL Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Metabolite:H+
CC Symporter (MHS) family (TC 2.A.1.6) family.
CC {ECO:0000256|ARBA:ARBA00008240}.
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DR EMBL; CP024847; AUR51903.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I7N605; -.
DR KEGG; nba:CUN60_06190; -.
DR OrthoDB; 6766492at2; -.
DR Proteomes; UP000236655; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR PANTHER; PTHR43528; ALPHA-KETOGLUTARATE PERMEASE; 1.
DR PANTHER; PTHR43528:SF6; CITRATE-PROTON SYMPORTER; 1.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00217; SUGAR_TRANSPORT_2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236655};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022847}.
FT TRANSMEM 7..30
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..66
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 108..132
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 144..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..247
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..317
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..349
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 361..383
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 389..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 6..416
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 417 AA; 45880 MW; 4F509C2156BC6549 CRC64;
MRRAHNVFNV AVGNFFEMYD FMVFGLYASY IAKSFFPNNN VYISLLLSFL TFGAGFLMRP
LGAIILGAYI DRHGRKKGLL LTLSLMAIGT ISIALTPDYA TIGVAAPIII LLGRLIQGFS
AGAELGGVSV YLAEIADKHN KGFFVSWQSA SQQMAIAIAA LFGYILNEIF AKPFMESFGW
RIPFIFGCLI LPVLFLQRSK LEESREFDTR KIHPSFKAII TSAIKNCGFL VACSFMVMLT
TVSFYMITAY TPTFAKIELG LSESKAFILT LIIALSNFIL LPLMGALSDK IGRAKQLLLF
SALFILTAYP VLLFVTKSNL YSSVIVGELW FSILYAGYNG AMVIALVEIV PKEIRSISFS
LAYSIATAIY GGFTPAIATQ LIHFTQNKAA PAIWLSFAAF CSLVIILRLS ARIRNAI
//
