ID   A0A2I7S9Y2_9CAUD        Unreviewed;       250 AA.
AC   A0A2I7S9Y2;
DT   28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT   28-MAR-2018, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   SubName: Full=Sir2 family protein {ECO:0000313|EMBL:AUS02704.1};
GN   ORFNames=NVP2275O_123 {ECO:0000313|EMBL:AUS02704.1};
OS   Vibrio phage 2.275.O._10N.286.54.E11.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes.
OX   NCBI_TaxID=1881285 {ECO:0000313|EMBL:AUS02704.1, ECO:0000313|Proteomes:UP000271093};
RN   [1] {ECO:0000313|EMBL:AUS02704.1, ECO:0000313|Proteomes:UP000271093}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kauffman K.M., Hussain F.A., Yang J., Arevalo P., Brown J.M., Chang W.K.,
RA   VanInsberghe D., Elsherbini J., Cutler M.B., Kelly L., Polz M.F.;
RT   "A major lineage of nontailed dsDNA viruses as unrecognized killers of
RT   marine bacteria.";
RL   Submitted (NOV-2017) to the EMBL/GenBank/DDBJ databases.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MG592671; AUS02704.1; -; Genomic_DNA.
DR   Proteomes; UP000271093; Genome.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.1600.10; SIR2/SIRT2 'Small Domain; 1.
DR   Gene3D; 3.40.50.1220; TPP-binding domain; 1.
DR   InterPro; IPR029035; DHS-like_NAD/FAD-binding_dom.
DR   InterPro; IPR003000; Sirtuin.
DR   InterPro; IPR026591; Sirtuin_cat_small_dom_sf.
DR   InterPro; IPR026590; Ssirtuin_cat_dom.
DR   PANTHER; PTHR11085:SF12; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL; 1.
DR   PANTHER; PTHR11085; NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED; 1.
DR   Pfam; PF02146; SIR2; 1.
DR   SUPFAM; SSF52467; DHS-like NAD/FAD-binding domain; 1.
DR   PROSITE; PS50305; SIRTUIN; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..250
FT                   /note="Deacetylase sirtuin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50305"
SQ   SEQUENCE   250 AA;  28167 MW;  ACB52C8A1618DD74 CRC64;
     MSHEPRLIIF SGAGLDAASG IPTFRDSNGL WEGNDVMEVC TMSTFEQNYE KVHRFYNQMR
     TALANVEPNS AHKFIAEMQD EYGAARVVNF TANVSDLLER ANVQNVRHVH GILTEIITDY
     KGPDHETKTV GYTEYDFEQD RIDARTFQPN CKPNVVFFGE MAPMYAEMDY ILQGLRPQDT
     FVIVGSTLEV NPVHHYAWGK DCYSVIINPS YKEGSESPLD IAGMTVTSAL SLTAEDGFEC
     IRDLIKKRMG
//