ID A0A2I8DPF8_9BURK Unreviewed; 483 AA.
AC A0A2I8DPF8;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cardiolipin synthase {ECO:0000313|EMBL:AUT49266.1};
GN ORFNames=C2U31_26730 {ECO:0000313|EMBL:AUT49266.1};
OS Achromobacter sp. AONIH1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=1758194 {ECO:0000313|EMBL:AUT49266.1, ECO:0000313|Proteomes:UP000236176};
RN [1] {ECO:0000313|Proteomes:UP000236176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AONIH1 {ECO:0000313|Proteomes:UP000236176};
RX PubMed=29437920;
RG NISC Comparative Sequencing Program;
RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P.,
RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J.,
RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.;
RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of
RT Bacterial Plasmids Conferring Carbapenem Resistance.";
RL MBio 9:e02011-e02017(2018).
RN [2] {ECO:0000313|Proteomes:UP000236176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AONIH1 {ECO:0000313|Proteomes:UP000236176};
RA Segre J.A., Mullikin J.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP026124; AUT49266.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I8DPF8; -.
DR KEGG; achr:C2U31_26730; -.
DR OrthoDB; 9762009at2; -.
DR Proteomes; UP000236176; Chromosome.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030572; F:phosphatidyltransferase activity; IEA:UniProt.
DR GO; GO:0032049; P:cardiolipin biosynthetic process; IEA:UniProt.
DR CDD; cd09157; PLDc_CLS_unchar2_1; 1.
DR CDD; cd09163; PLDc_CLS_unchar2_2; 1.
DR Gene3D; 3.30.870.10; Endonuclease Chain A; 2.
DR InterPro; IPR025202; PLD-like_dom.
DR InterPro; IPR001736; PLipase_D/transphosphatidylase.
DR PANTHER; PTHR21248; CARDIOLIPIN SYNTHASE; 1.
DR PANTHER; PTHR21248:SF22; PHOSPHOLIPASE D; 1.
DR Pfam; PF13091; PLDc_2; 2.
DR SMART; SM00155; PLDc; 2.
DR SUPFAM; SSF56024; Phospholipase D/nuclease; 2.
DR PROSITE; PS50035; PLD; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000236176};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 40..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..246
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
FT DOMAIN 396..423
FT /note="PLD phosphodiesterase"
FT /evidence="ECO:0000259|PROSITE:PS50035"
SQ SEQUENCE 483 AA; 52589 MW; BFCF08B3ABF496AF CRC64;
MDLHAILLEY WPHIVFVVSL AAGAGAAVHA AMTKQDVRSA IGWVGLTLLS PLFGALIYVV
AGINRIRKTR LSQQRDEAML EDAAQVETAP VDVAPISGSQ FASLKVLGDQ VSRFRLLGGN
AVLPLAGGDE AYPAMLQAIR DASHAVAMQS YIFDNDPIGR EMAQALIEAH ERGVQVRVLI
DAIGSRYSRP PIVRMLARGG VPVARFMTNP LGVLRMPYAN LRSHRKILVV DGRVGFTGGM
NVRAAFVTAL SGADTNADTH FRLEGPIVTQ LMSVFAHDWN FTTHESLPQR PWFDPDAAPA
GSIPVRCVPS GPDRALGSTH NMLLGALAVA QRHVRIQSPY FLPDQTLIGA LATAARRGVV
VDIVIPGKNN LRLVDYAMTA QLDQVVRTGC RVWRSHGAFD HSKLMTVDDA WTYAGSSNLD
PRSLRLNFEL DTEIYDPGVS HGLGARIDGI IGQARRVTLE DLQQAPFAKR LRNKVIWLAT
PYL
//
