ID A0A2I8DRL2_9BURK Unreviewed; 530 AA.
AC A0A2I8DRL2;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=diguanylate cyclase {ECO:0000256|ARBA:ARBA00012528};
DE EC=2.7.7.65 {ECO:0000256|ARBA:ARBA00012528};
GN ORFNames=C2U31_08975 {ECO:0000313|EMBL:AUT50033.1};
OS Achromobacter sp. AONIH1.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Alcaligenaceae; Achromobacter.
OX NCBI_TaxID=1758194 {ECO:0000313|EMBL:AUT50033.1, ECO:0000313|Proteomes:UP000236176};
RN [1] {ECO:0000313|Proteomes:UP000236176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AONIH1 {ECO:0000313|Proteomes:UP000236176};
RX PubMed=29437920;
RG NISC Comparative Sequencing Program;
RA Weingarten R.A., Johnson R.C., Conlan S., Ramsburg A.M., Dekker J.P.,
RA Lau A.F., Khil P., Odom R.T., Deming C., Park M., Thomas P.J.,
RA Henderson D.K., Palmore T.N., Segre J.A., Frank K.M.;
RT "Genomic Analysis of Hospital Plumbing Reveals Diverse Reservoir of
RT Bacterial Plasmids Conferring Carbapenem Resistance.";
RL MBio 9:e02011-e02017(2018).
RN [2] {ECO:0000313|Proteomes:UP000236176}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AONIH1 {ECO:0000313|Proteomes:UP000236176};
RA Segre J.A., Mullikin J.;
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP026124; AUT50033.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I8DRL2; -.
DR KEGG; achr:C2U31_08975; -.
DR OrthoDB; 9813903at2; -.
DR Proteomes; UP000236176; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd18773; PDC1_HK_sensor; 1.
DR CDD; cd12912; PDC2_MCP_like; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR033479; dCache_1.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR029151; Sensor-like_sf.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR PANTHER; PTHR45138:SF9; DIGUANYLATE CYCLASE DGCM-RELATED; 1.
DR PANTHER; PTHR45138; REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM; 1.
DR Pfam; PF02743; dCache_1; 1.
DR Pfam; PF00990; GGDEF; 1.
DR SMART; SM00267; GGDEF; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF103190; Sensory domain-like; 2.
DR PROSITE; PS50887; GGDEF; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000236176};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 387..519
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
SQ SEQUENCE 530 AA; 58446 MW; D94B76992FD0D1E2 CRC64;
MIRIDLRRLI LWISLLSIML VLAGGLHASY LVQRDLLLHN AQEDNRAYAS KLAATTEYFL
NDLRRYLAFS AEMLADMQAH PELMAEETRR QETQLGHFNS SFIVSPQGKV LSASASVPDL
LGRQMHSTAA QDAIQTQRPT ISEPFQGRSG RWLILYTHPI FSADKRYIGY IAGTLYLHQD
NVLDRLLGQH FHRDDSVLRV MDRNGTLIYD RDRSMLGKPA AELQALAPAL RGETGELRFV
DAHGREMLAG YAPVPSTGWS LIAQRPVAGT LQPLSDLLLA TARNTLPLLL LSIASLWLLS
RLIAKPLGEL AGFAKRMQDL DSADGIRGVR SWYFEATQLK RALLMGLASM HHKMRDLRRK
SATDTLTGLL NRRGLEEAMA MLQAEDTPVA IVVIDIDHFK NINDRYGHAA GDRALQRLAR
QMADSARASD TLARAGGEEF VMLLPGVPMA AAVAAAHRLR LKVATSPDPD LSAHPITLSA
GVAHYPTHGA TLEAVYQRAD QALYYAKNHG RNAVAAADDL VRGGLRSTLP
//
