ID A0A2I8VNK1_9EURY Unreviewed; 383 AA.
AC A0A2I8VNK1;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE SubName: Full=2-oxo-3-methylvalerate dehydrogenase E1 component subunit alpha {ECO:0000313|EMBL:AUV82679.1};
GN ORFNames=C2R22_14355 {ECO:0000313|EMBL:AUV82679.1};
OS Salinigranum rubrum.
OC Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Haloferacales;
OC Halorubraceae; Salinigranum.
OX NCBI_TaxID=755307 {ECO:0000313|EMBL:AUV82679.1, ECO:0000313|Proteomes:UP000236584};
RN [1] {ECO:0000313|EMBL:AUV82679.1, ECO:0000313|Proteomes:UP000236584}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=GX10 {ECO:0000313|EMBL:AUV82679.1,
RC ECO:0000313|Proteomes:UP000236584};
RA Han S.;
RT "Complete genome sequence of Salinigranum rubrum GX10T, an extremely
RT halophilic archaeon isolated from a marine solar saltern.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP026309; AUV82679.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I8VNK1; -.
DR KEGG; srub:C2R22_14355; -.
DR OrthoDB; 25266at2157; -.
DR Proteomes; UP000236584; Chromosome.
DR GO; GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR GO; GO:1901576; P:organic substance biosynthetic process; IEA:UniProt.
DR GO; GO:0044272; P:sulfur compound biosynthetic process; IEA:UniProt.
DR CDD; cd02000; TPP_E1_PDC_ADC_BCADC; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR001017; DH_E1.
DR InterPro; IPR029061; THDP-binding.
DR PANTHER; PTHR43380; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43380:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT ALPHA, MITOCHONDRIAL; 1.
DR Pfam; PF00676; E1_dh; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000236584}.
FT DOMAIN 56..339
FT /note="Dehydrogenase E1 component"
FT /evidence="ECO:0000259|Pfam:PF00676"
SQ SEQUENCE 383 AA; 42526 MW; 50DB3DFD649264B5 CRC64;
MRGTTRPDSE RAPTVEGLSQ SDLTVETYQV VAPDGTVREG EVPAFTDDQF RELYRWLLLQ
RTFDDRMTKL QRRGQLGTYA SGRGQEASIV GSGFALDDGD WLFPYGREAG ALLLHGLSMR
DLVMYWRGIE DASRMEGANV FGVAIAIGSH VPLATGKAWG MQLDGDDTVA FANLGDGATS
TGAFHEGLNL AGVLSVPAVF FCQNNQYAIS LPFEKQTGAD TVAQKALAYG VDGIRVDGND
VLAVYNAVAT ARRRALDGRP TLVEAVTYRR AAHTTSDDPS RYREQAEVDE WAERDPLDRY
RGFLAGRGLL DDVDEERVQA EVDELFDEAV AAADDYPHRD LAEMFVHLYE EPTPELESQL
AWYRDFLDTH PEMAEYIHQR ERG
//
