ID A0A2I9DHA3_9DEIO Unreviewed; 411 AA.
AC A0A2I9DHA3;
DT 28-MAR-2018, integrated into UniProtKB/TrEMBL.
DT 28-MAR-2018, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Major facilitator transporter {ECO:0000313|EMBL:GBF05558.1};
GN ORFNames=DAERI_050067 {ECO:0000313|EMBL:GBF05558.1};
OS Deinococcus aerius.
OC Bacteria; Deinococcota; Deinococci; Deinococcales; Deinococcaceae;
OC Deinococcus.
OX NCBI_TaxID=200253 {ECO:0000313|EMBL:GBF05558.1, ECO:0000313|Proteomes:UP000236569};
RN [1] {ECO:0000313|Proteomes:UP000236569}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TR0125 {ECO:0000313|Proteomes:UP000236569};
RA Satoh K., Arai H., Sanzen T., Kawaguchi Y., Hayashi H., Yokobori S.,
RA Yamagishi A., Oono Y., Narumi I.;
RT "Draft Genome Sequence of the Radioresistant Bacterium Deinococcus aerius
RT TR0125, Isolated from the Higher Atmosphere above Japan.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:GBF05558.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BFAG01000005; GBF05558.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A2I9DHA3; -.
DR OrthoDB; 9775268at2; -.
DR Proteomes; UP000236569; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR CDD; cd06173; MFS_MefA_like; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR010290; TM_effector.
DR PANTHER; PTHR23513; INTEGRAL MEMBRANE EFFLUX PROTEIN-RELATED; 1.
DR PANTHER; PTHR23513:SF6; MULTIDRUG EFFLUX PUMP TAP; 1.
DR Pfam; PF05977; MFS_3; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 85..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 160..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 221..246
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..272
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 284..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 308..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 374..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 218..411
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 411 AA; 42860 MW; 9F578C0A7DF3DB73 CRC64;
MRVWRAGPTF RRLWLASTSA NIGDGIGKTA LPLLVASISR DPIIVASLSA FAALPGLVFT
LPFGALIDRL DRRTLLLVAH TARGVLLGLL ALAIFAGHLH VALLYGVAFV LGTAETLADG
TAETLVPSLV GKEQLEDANG ALYATSVTSN EFVGPPLGGL LFAAFPGLPF LVNALSFLGS
TALISTLPRR PAPRGVTRER WWREVTDGLR WLWSHALLRS VALLMALTTL LDAAVFALFV
LFATALPGVG PVGYGLLLTA GAVGHILGSL LSPYVSRRFG AGRTVLGSVF VLGLVYLGLS
VLRAPPLLAA LLVLDGLNLG LSGVVKVTLR QRLVPPELLG RVGGAYRFIV AGAAPLGAFL
GGVLGQTLGL RETFAVAGGL ALVVAVLFVG RVNNRAVARA QERVYGSPPL S
//
